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BMCBI
2011
13 years 11 days ago
RedundancyMiner: De-replication of redundant GO categories in microarray and proteomics analysis
Background: The Gene Ontology (GO) Consortium organizes genes into hierarchical categories based on biological process, molecular function and subcellular localization. Tools such...
Barry Zeeberg, Hongfang Liu, Ari B. Kahn, Martin E...
BMCBI
2011
13 years 11 days ago
Comparing genotyping algorithms for Illumina's Infinium whole-genome SNP BeadChips
Background: Illumina’s Infinium SNP BeadChips are extensively used in both small and large-scale genetic studies. A fundamental step in any analysis is the processing of raw all...
Matthew E. Ritchie, Ruijie Liu, Benilton Carvalho,...
BMCBI
2011
13 years 11 days ago
LabKey Server: An open source platform for scientific data integration, analysis and collaboration
Background: Broad-based collaborations are becoming increasingly common among disease researchers. For example, the Global HIV Enterprise has united cross-disciplinary consortia t...
Elizabeth K. Nelson, Britt Piehler, Josh Eckels, A...
BMCBI
2011
12 years 12 months ago
SAQC: SNP array quality control
Background: Genome-wide single-nucleotide polymorphism (SNP) arrays containing hundreds of thousands of SNPs from the human genome have proven useful for studying important human ...
Hsin-Chou Yang, Hsin-Chi Lin, Meijyh Kang, Chun-Ho...
BMCBI
2011
12 years 12 months ago
PheMaDB: A solution for storage, retrieval, and analysis of high throughput phenotype data
Background: OmniLog™ phenotype microarrays (PMs) have the capability to measure and compare the growth responses of biological samples upon exposure to hundreds of growth condit...
Wenling E. Chang, Keri Sarver, Brandon W. Higgs, T...