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BMCBI
2005
13 years 5 months ago
2005
Background -: Sequencing of EST and BAC end datasets is no longer limited to large research groups. Drops in per-base pricing have made high throughput sequencing accessible to in...
BMCBI
2005
13 years 5 months ago
2005
Background: Structure-dependent substitution matrices increase the accuracy of sequence alignments when the 3D structure of one sequence is known, and are successful e.g. in fold ...
BMCBI
2005
13 years 5 months ago
2005
Background: Sequence comparison by alignment is a fundamental tool of molecular biology. In this paper we show how a number of sequence comparison tasks, including the detection o...
BMCBI
2005
13 years 5 months ago
2005
Background: Accurate diagnosis of cancer subtypes remains a challenging problem. Building classifiers based on gene expression data is a promising approach; yet the selection of n...
BMCBI
2005
13 years 5 months ago
2005
Background: Microarray analysis has become a widely used technique for the study of geneexpression patterns on a genomic scale. As more and more laboratories are adopting microarr...