A major challenge in computational systems biology is the articulation of a biological process in a form which can be understood by the biologist yet is amenable to computational e...
Systems of ordinary differential equations (ODEs) are often used to model the dynamics of complex biological pathways. We construct a discrete state model as a probabilistic appro...
Molecular noise, which arises from the randomness of the discrete events in the cell, significantly influences fundamental biological processes. Discrete-state continuous-time st...
Abstract. In systems biology, the number of models of cellular processes increases rapidly, but re-using models in different contexts or for different questions remains a challengi...
Circadian clocks are biochemical networks, present in nearly all living organisms, whose function is to regulate the expression of specific mRNAs and proteins to synchronise rhyth...
Ozgur E. Akman, Federica Ciocchetta, Andrea Degasp...