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BMCBI
2006
110views more  BMCBI 2006»
13 years 5 months ago
Design of a combinatorial DNA microarray for protein-DNA interaction studies
Background: Discovery of precise specificity of transcription factors is an important step on the way to understanding the complex mechanisms of gene regulation in eukaryotes. Rec...
Julian Mintseris, Michael B. Eisen
BMCBI
2005
142views more  BMCBI 2005»
13 years 5 months ago
transAlign: using amino acids to facilitate the multiple alignment of protein-coding DNA sequences
Background: Alignments of homologous DNA sequences are crucial for comparative genomics and phylogenetic analysis. However, multiple alignment represents a computationally difficu...
Olaf R. P. Bininda-Emonds
BMCBI
2006
116views more  BMCBI 2006»
13 years 5 months ago
MICA: desktop software for comprehensive searching of DNA databases
Background: Molecular biologists work with DNA databases that often include entire genomes. A common requirement is to search a DNA database to find exact matches for a nondegener...
William A. Stokes, Benjamin S. Glick
BMCBI
2006
95views more  BMCBI 2006»
13 years 5 months ago
Predicting DNA-binding sites of proteins from amino acid sequence
Background: Understanding the molecular details of protein-DNA interactions is critical for deciphering the mechanisms of gene regulation. We present a machine learning approach f...
Changhui Yan, Michael Terribilini, Feihong Wu, Rob...
ARTMED
2005
87views more  ARTMED 2005»
13 years 5 months ago
Fuzzy attributes of a DNA complex: Development of a fuzzy inference engine for codon-"junk" codon delineation
Codons refer to those parts in a DNA complex encoded towards forming a desired set of proteins. Also coexist in the DNA are noncodons (or "junk" codons) whose functions ...
Tomás Arredondo Vidal, Perambur S. Neelakan...