The most parsimonous distances calculated in pairwise gene order comparisons cannot accurately reflect the true number of events separating two species, unless the number of chan...
: Markov models have been proposed for the classification of DNA-motifs using generative approaches for parameter learning. Here, we propose to apply the discriminative paradigm fo...
Jan Grau, Jens Keilwagen, Alexander E. Kel, Ivo Gr...
: The recent availability of large data sets of protein- protein-interactions (PPIs) from various species offers new opportunities for functional genomics and proteomics. We descri...
: There are several models for the evolutionary process forming a species tree. We examine the Birth-and-Death model (BDM), the Proportional-to-Distinguishable Arrangements (PDA) m...