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JCB
2002
102views more  JCB 2002»
13 years 4 months ago
A Lower Bound on the Reversal and Transposition Diameter
One possible model to study genome evolution is to represent genomes as permutations of genes and compute distances based on the minimum number of certain operations (rearrangemen...
João Meidanis, Maria Emilia Telles Walter, ...
JCB
2002
111views more  JCB 2002»
13 years 4 months ago
A General Edit Distance between RNA Structures
Arc-annotated sequences are useful in representing the structural information of RNA sequences. In general, RNA secondary and tertiary structures can be represented as a set of ne...
Tao Jiang, Guohui Lin, Bin Ma, Kaizhong Zhang
JCB
2002
131views more  JCB 2002»
13 years 4 months ago
Modeling and Simulation of Genetic Regulatory Systems: A Literature Review
In order to understand the functioning of organisms on the molecular level, we need to know which genes are expressed, when and where in the organism, and to which extent. The reg...
Hidde de Jong
JCB
2002
93views more  JCB 2002»
13 years 4 months ago
Unfolding of Microarray Data
The use of DNA microarrays for the analysis of complex biological samples is becoming a mainstream part of biomedical research. One of the most commonly used methods compares the ...
Andrew B. Goryachev, Pascale F. Macgregor, Aled M....
JCB
2002
116views more  JCB 2002»
13 years 4 months ago
A Novel Approach to Remote Homology Detection: Jumping Alignments
We describe a new algorithm for protein classi cation and the detection of remote homologs. The rationale is to exploit both vertical and horizontal information of a multiple alig...
Rainer Spang, Marc Rehmsmeier, Jens Stoye