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JCB
2007
191views more  JCB 2007»
13 years 5 months ago
Bayesian Haplotype Inference via the Dirichlet Process
The problem of inferring haplotypes from genotypes of single nucleotide polymorphisms (SNPs) is essential for the understanding of genetic variation within and among populations, ...
Eric P. Xing, Michael I. Jordan, Roded Sharan
JCB
2007
107views more  JCB 2007»
13 years 5 months ago
Effects of Long-Range Correlations in DNA on Sequence Alignment Score Statistics
Long-range correlations in genomic base composition are a ubiquitous statistical feature among many eukaryotic genomes. In this article, these correlations are shown to substantia...
Philipp W. Messer, Ralf Bundschuh, Martin Vingron,...
JCB
2007
168views more  JCB 2007»
13 years 5 months ago
Fast Molecular Shape Matching Using Contact Maps
In this paper, we study the problem of computing the similarity of two protein structures ring their contact-map overlap. Contact-map overlap abstracts the problem of computing th...
Pankaj K. Agarwal, Nabil H. Mustafa, Yusu Wang
JCB
2007
83views more  JCB 2007»
13 years 5 months ago
Evolutionary Networks in the Formatted Protein Sequence Space
In our recent work, a new approach to establish sequence relatedness, by walking through the protein sequence space, was introduced. The sequence space is built from 20 amino acid...
Zakharia M. Frenkel, Edward N. Trifonov
JCB
2007
106views more  JCB 2007»
13 years 5 months ago
Clustered Sequence Representation for Fast Homology Search
We present a novel approach to managing redundancy in sequence databanks such as GenBank. We store clusters of near-identical sequences as a representative union-sequence and a se...
Michael Cameron, Yaniv Bernstein, Hugh E. Williams