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JCNS
2000
84views more  JCNS 2000»
13 years 4 months ago
Nonlinear Thermodynamic Models of Voltage-Dependent Currents
Hodgkin and Huxley provided the first quantitative description of voltage-dependent currents and adjusted their model to experimental data using empirical functions of voltage. A p...
Alain Destexhe, John R. Huguenard
JCNS
2000
64views more  JCNS 2000»
13 years 4 months ago
A Simple Mathematical Model of Second-Messenger Mediated Slow Excitatory
We have developed a novel and simple mathematical model of a slow excitatory postsynaptic potential ased on an abstraction of the processes of activation, inactivation, and summati...
P. P. Bertrand, E. A. Thomas, W. A. A. Kunze, J. C...
JCNS
2000
73views more  JCNS 2000»
13 years 4 months ago
Models of Calmodulin Trapping and CaM Kinase II Activation in a Dendritic Spine
Activation of calcium/calmodulin-dependent protein kinase II (CaMKII) by calmodulin following calcium entry into the cell is important for long-term potentiation (LTP). Here a mode...
William Holmes
JCNS
2000
142views more  JCNS 2000»
13 years 4 months ago
A Temporal Mechanism for Generating the Phase Precession of Hippocampal Place Cells
The phase relationship between the activity of hippocampal place cells and the hippocampal theta rhythm systematically precesses as the animal runs through the region in an environ...
Amitabha Bose, Victoria Booth, Michael Recce
JCNS
2000
165views more  JCNS 2000»
13 years 4 months ago
A Population Density Approach That Facilitates Large-Scale Modeling of Neural Networks: Analysis and an Application to Orientati
We explore a computationally efficient method of simulating realistic networks of neurons introduced by Knight, Manin, and Sirovich (1996) in which integrate-and-fire neurons are ...
Duane Q. Nykamp, Daniel Tranchina