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BMCBI
2007
237views more  BMCBI 2007»
13 years 5 months ago
FLAME, a novel fuzzy clustering method for the analysis of DNA microarray data
Background: Data clustering analysis has been extensively applied to extract information from gene expression profiles obtained with DNA microarrays. To this aim, existing cluster...
Limin Fu, Enzo Medico
BMCBI
2008
202views more  BMCBI 2008»
13 years 5 months ago
Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
BMCBI
2010
190views more  BMCBI 2010»
13 years 5 months ago
Sample size and statistical power considerations in high-dimensionality data settings: a comparative study of classification alg
Background: Data generated using `omics' technologies are characterized by high dimensionality, where the number of features measured per subject vastly exceeds the number of...
Yu Guo, Armin Graber, Robert N. McBurney, Raji Bal...
BMCBI
2008
158views more  BMCBI 2008»
13 years 5 months ago
Real value prediction of protein solvent accessibility using enhanced PSSM features
Background: Prediction of protein solvent accessibility, also called accessible surface area (ASA) prediction, is an important step for tertiary structure prediction directly from...
Darby Tien-Hao Chang, Hsuan-Yu Huang, Yu-Tang Syu,...
BMCBI
2007
119views more  BMCBI 2007»
13 years 5 months ago
Efficacy of different protein descriptors in predicting protein functional families
Background: Sequence-derived structural and physicochemical descriptors have frequently been used in machine learning prediction of protein functional families, thus there is a ne...
Serene A. K. Ong, Hong Huang Lin, Yu Zong Chen, Ze...