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BMCBI
2010
165views more  BMCBI 2010»
13 years 5 months ago
MTar: a computational microRNA target prediction architecture for human transcriptome
Background: MicroRNAs (miRNAs) play an essential task in gene regulatory networks by inhibiting the expression of target mRNAs. As their mRNA targets are genes involved in importa...
Vinod Chandra, Reshmi Girijadevi, Achuthsankar S. ...
BMCBI
2007
226views more  BMCBI 2007»
13 years 5 months ago
MiRFinder: an improved approach and software implementation for genome-wide fast microRNA precursor scans
Background: MicroRNAs (miRNAs) are recognized as one of the most important families of noncoding RNAs that serve as important sequence-specific post-transcriptional regulators of ...
Ting-Hua Huang, Bin Fan, Max F. Rothschild, Zhi-Li...
ALMOB
2008
69views more  ALMOB 2008»
13 years 5 months ago
Learning from positive examples when the negative class is undetermined- microRNA gene identification
Background: The application of machine learning to classification problems that depend only on positive examples is gaining attention in the computational biology community. We an...
Malik Yousef, Segun Jung, Louise C. Showe, Michael...
ICONIP
2010
13 years 2 months ago
Exploring Features and Classifiers to Classify MicroRNA Expression Profiles of Human Cancer
Recently, some non-coding small RNAs, known as microRNAs (miRNA), have drawn a lot of attention to identify their role in gene regulation and various biological processes. The miRN...
Kyung-Joong Kim, Sung-Bae Cho
IDEAL
2005
Springer
13 years 10 months ago
Predictive Vaccinology: Optimisation of Predictions Using Support Vector Machine Classifiers
Promiscuous human leukocyte antigen (HLA) binding peptides are ideal targets for vaccine development. Existing computational models for prediction of promiscuous peptides used hidd...
Ivana Bozic, Guanglan Zhang, Vladimir Brusic