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TCBB
2010
166views more  TCBB 2010»
13 years 3 months ago
Approximate Maximum Parsimony and Ancestral Maximum Likelihood
— We explore the maximum parsimony (MP) and ancestral maximum likelihood (AML) criteria in phylogenetic tree reconstruction. Both problems are NP hard, so we seek approximate sol...
Noga Alon, Benny Chor, Fabio Pardi, Anat Rapoport
TCBB
2010
137views more  TCBB 2010»
13 years 1 days ago
The Metropolized Partial Importance Sampling MCMC Mixes Slowly on Minimum Reversal Rearrangement Paths
Markov chain Monte Carlo has been the standard technique for inferring the posterior distribution of genome rearrangement scenarios under a Bayesian approach. We present here a neg...
István Miklós, Bence Melykuti, Krist...
TCBB
2010
114views more  TCBB 2010»
13 years 3 months ago
Cache-Oblivious Dynamic Programming for Bioinformatics
— We present efficient cache-oblivious algorithms for some well-studied string problems in bioinformatics including the longest common subsequence, global pairwise sequence alig...
Rezaul Alam Chowdhury, Hai-son Le, Vijaya Ramachan...
TCBB
2010
137views more  TCBB 2010»
13 years 3 months ago
Alignments of RNA Structures
— We describe a theoretical unifying framework to express comparison of RNA structures, which we call alignment hierarchy. This framework relies on the definition of common supe...
Guillaume Blin, Alain Denise, Serge Dulucq, Claire...
TCBB
2010
89views more  TCBB 2010»
13 years 3 months ago
Model Composition for Macromolecular Regulatory Networks
—Models of regulatory networks become more difficult to construct and understand as they grow in size and complexity. Large models are usually built up from smaller models, repre...
Ranjit Randhawa, Clifford A. Shaffer, John J. Tyso...