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WABI
2010
Springer
160views Bioinformatics» more  WABI 2010»
8 years 3 months ago
Genomic Distance with DCJ and Indels
The double cut and join (DCJ) operation, introduced by Yancopoulos, Attie and Friedberg in 2005, allows one to represent most rearrangement events in genomes. However, a DCJ cannot...
Marília D. V. Braga, Eyla Willing, Jens Sto...
WABI
2010
Springer
143views Bioinformatics» more  WABI 2010»
8 years 3 months ago
Swiftly Computing Center Strings
The center string (or closest string) problem is a classical computer science problem with important applications in computational biology. Given k input strings and a distance thr...
Franziska Hufsky, Léon Kuchenbecker, Kathar...
WABI
2010
Springer
172views Bioinformatics» more  WABI 2010»
8 years 3 months ago
Fast Mapping and Precise Alignment of AB SOLiD Color Reads to Reference DNA
Abstract. Applied Biosystems’ SOLiD system offers a low-cost alternative to the traditional Sanger method of DNA sequencing. We introduce two main algorithms of mapping SOLiD’...
Miklós Csürös, Szilveszter Juhos,...
WABI
2010
Springer
124views Bioinformatics» more  WABI 2010»
8 years 3 months ago
Improved Orientations of Physical Networks
Abstract. The orientation of physical networks is a prime task in deciphering the signaling-regulatory circuitry of the cell. One manifestation of this computational task is as a m...
Iftah Gamzu, Danny Segev, Roded Sharan
WABI
2010
Springer
177views Bioinformatics» more  WABI 2010»
8 years 3 months ago
Estimation of Alternative Splicing isoform Frequencies from RNA-Seq Data
In this paper we present a novel expectation-maximization algorithm for inference of alternative splicing isoform frequencies from high-throughput transcriptome sequencing (RNA-Seq...
Marius Nicolae, Serghei Mangul, Ion I. Mandoiu, Al...
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