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PRIB
2009
Springer
120views Bioinformatics» more  PRIB 2009»
11 years 4 months ago
Knowledge-Guided Docking of WW Domain Proteins and Flexible Ligands
Studies of interactions between protein domains and ligands are important in many aspects such as cellular signaling. We present a knowledge-guided approach for docking protein dom...
Haiyun Lu, Hao Li, Shamima Banu Bte Sm Rashid, Wee...
GCB
2009
Springer
105views Biometrics» more  GCB 2009»
11 years 5 months ago
Maximum Likelihood Estimation of Weight Matrices for Targeted Homology Search
: Genome annotation relies to a large extent on the recognition of homologs to already known genes. The starting point for such protocols is a collection of known sequences from on...
Peter Menzel, Jan Gorodkin, Peter F. Stadler
GCB
2009
Springer
141views Biometrics» more  GCB 2009»
11 years 5 months ago
Discovering Temporal Patterns of Differential Gene Expression in Microarray Time Series
: A wealth of time series of microarray measurements have become available over recent years. Several two-sample tests for detecting differential gene expression in these time seri...
Oliver Stegle, Katherine J. Denby, David L. Wild, ...
GCB
2009
Springer
180views Biometrics» more  GCB 2009»
11 years 5 months ago
2D Projections of RNA Folding Landscapes
Abstract: The analysis of RNA folding landscapes yields insights into the kinetic folding behavior not available from classical structure prediction methods. This is especially imp...
Ronny Lorenz, Christoph Flamm, Ivo L. Hofacker
GCB
2009
Springer
481views Biometrics» more  GCB 2009»
11 years 5 months ago
CUDA-based Multi-core Implementation of MDS-based Bioinformatics Algorithms
: Solving problems in bioinformatics often needs extensive computational power. Current trends in processor architecture, especially massive multi-core processors for graphic cards...
Thilo Fester, Falk Schreiber, Marc Strickert
CSEE
2009
Springer
11 years 5 months ago
Software Engineering Education for Bioinformatics
As software engineering educators, it is important for us to realize the increasing domainspecificity of software, and incorporate these changes in our design of teaching material...
Medha Umarji, Carolyn B. Seaman, Akif Günes K...
ISBRA
2009
Springer
11 years 5 months ago
Using Gene Expression Modeling to Determine Biological Relevance of Putative Regulatory Networks
Identifying gene regulatory networks from high-throughput gene expression data is one of the most important goals of bioinformatics, but it remains difficult to define what makes a...
Peter Larsen, Yang Dai
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