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BIBM
2009
IEEE
155views Bioinformatics» more  BIBM 2009»
13 years 10 months ago
Towards Reliable Isoform Quantification Using RNA-Seq Data
Background: In eukaryotes, alternative splicing often generates multiple splice variants from a single gene. Here weexplore the use of RNA sequencing (RNA-Seq) datasets to address...
Brian E. Howard, Steffen Heber
BIBM
2009
IEEE
192views Bioinformatics» more  BIBM 2009»
13 years 10 months ago
A Multi-task Feature Selection Filter for Microarray Classification
A major challenge in microarray classification and biomarker discovery is dealing with small-sample high-dimensional data where the number of genes used as features is typically o...
Liang Lan, Slobodan Vucetic
BIBM
2009
IEEE
151views Bioinformatics» more  BIBM 2009»
13 years 10 months ago
Detection of Gene Orthology Based on Protein-Protein Interaction Networks
Abstract—Ortholog detection methods present a powerful approach for finding genes that participate in similar biological processes across different organisms, extending our unde...
Fadi Towfic, M. Heather West Greenlee, Vasant Hona...
BIBM
2009
IEEE
206views Bioinformatics» more  BIBM 2009»
13 years 10 months ago
Application of Kernel Functions for Accurate Similarity Search in Large Chemical Databases
Background: Similaritysearch in chemical structure databases is an important problem with many applications in chemical genomics, drug design, and efficient chemical probe screeni...
Xiaohong Wang, Jun Huan, Aaron M. Smalter, Gerald ...
BIBM
2009
IEEE
206views Bioinformatics» more  BIBM 2009»
13 years 10 months ago
ChemAlign: Biologically Relevant Multiple Sequence Alignment Using Physicochemical Properties
—We present a new algorithm, ChemAlign, that uses physicochemical properties and secondary structure elements to create biologically relevant multiple sequence alignments (MSAs)....
Hyrum Carroll, Mark J. Clement, Quinn Snell, David...
BIBM
2009
IEEE
218views Bioinformatics» more  BIBM 2009»
13 years 10 months ago
Real-Time Non-rigid Registration of Medical Images on a Cooperative Parallel Architecture
Abstract—Unacceptable execution time of Non-rigid registration (NRR) often presents a major obstacle to its routine clinical use. Parallel computing is an effective way to accele...
Yixun Liu, Andriy Fedorov, Ron Kikinis, Nikos Chri...
BIBM
2009
IEEE
127views Bioinformatics» more  BIBM 2009»
13 years 10 months ago
A Device for Detecting and Counting Bites of Food Taken by a Person during Eating
—We introduce methods for detecting in real-time information concerning bites taken during a meal. Our methods use an orientation sensor placed on the wrist of a user, and analyz...
Yujie Dong, Adam Hoover, Eric Muth
BIBE
2009
IEEE
210views Bioinformatics» more  BIBE 2009»
13 years 10 months ago
Analysis of Autism Prevalence and Neurotoxins Using Combinatorial Fusion and Association Rule Mining
- The increase in autism prevalence has been the motivation for much research which has produced various theories for its causation. Genetic and environmental factors have been inv...
Christina Schweikert, Yanjun Li, David Dayya, Davi...
BIBE
2009
IEEE
137views Bioinformatics» more  BIBE 2009»
13 years 10 months ago
Multi-Modal Registration of Embryonic Images for In Vitro Fertilization
This paper presents a robust and fully automated registration algorithm for alignment of embryonic images taken by Optical Quadrature Microscopy (OQM) and Differential Interferenc...
Chia-Ling Tsai, Su-Ching Liang, William Warger, Ch...