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BIBM
2010
IEEE
156views Bioinformatics» more  BIBM 2010»
9 years 5 months ago
Truncation of protein sequences for fast profile alignment with application to subcellular localization
We have recently found that the computation time of homology-based subcellular localization can be substantially reduced by aligning profiles up to the cleavage site positions of s...
Man-Wai Mak, Wei Wang, Sun-Yuan Kung
BIBM
2010
IEEE
222views Bioinformatics» more  BIBM 2010»
9 years 5 months ago
CEO a cloud epistasis computing model in GWAS
The 1000 Genome project has made available a large number of single nucleotide polymorphisms (SNPs) for genome-wide association studies (GWAS). However, the large number of SNPs ha...
Zhengkui Wang, Yue Wang, Kian-Lee Tan, Limsoon Won...
BIBM
2010
IEEE
151views Bioinformatics» more  BIBM 2010»
9 years 5 months ago
Rex: A toolset for reproducing software experiments
Being able to reproduce experiments is the cornerstone of the scientific method. Software experiments are hard to reproduce even if identical hardware is available because externa...
Somu Perianayagam, Gregory R. Andrews, John H. Har...
BIBM
2010
IEEE
221views Bioinformatics» more  BIBM 2010»
9 years 5 months ago
Overcoming drug resistance by co-targeting
Marzieh Ayati, Golnaz Taheri, Shahriar Arab, Limso...
BIBM
2010
IEEE
144views Bioinformatics» more  BIBM 2010»
9 years 5 months ago
Identification and quantification of abundant species from pyrosequences of 16S rRNA by consensus alignment
16S rRNA gene profiling has recently been boosted by the development of pyrosequencing methods. A common analysis is to group pyrosequences into Operational Taxonomic Units (OTUs),...
Yuzhen Ye
WABI
2010
Springer
178views Bioinformatics» more  WABI 2010»
9 years 6 months ago
Haplotype Inference on Pedigrees with Recombinations and Mutations
Abstract. Haplotype Inference (HI) is a computational challenge of crucial importance in a range of genetic studies, such as functional genomics, pharmacogenetics and population ge...
Yuri Pirola, Paola Bonizzoni, Tao Jiang
WABI
2010
Springer
141views Bioinformatics» more  WABI 2010»
9 years 6 months ago
An Experimental Study of Quartets MaxCut and Other Supertree Methods
Although many supertree methods have been developed in the last few decades, none has been shown to produce more accurate trees than the popular Matrix Representation with Parsimon...
M. Shel Swenson, Rahul Suri, C. Randal Linder, Tan...
WABI
2010
Springer
188views Bioinformatics» more  WABI 2010»
9 years 6 months ago
Prediction of RNA Secondary Structure Including Kissing Hairpin Motifs
Abstract. We present three heuristic strategies for folding RNA sequences into secondary structures including kissing hairpin motifs. The new idea is to construct a kissing hairpin...
Corinna Theis, Stefan Janssen, Robert Giegerich
WABI
2010
Springer
170views Bioinformatics» more  WABI 2010»
9 years 6 months ago
Haplotypes versus Genotypes on Pedigrees
Abstract. Genome sequencing will soon produce haplotype data for individuals. For pedigrees of related individuals, sequencing appears to be an attractive alternative to genotyping...
Bonnie Kirkpatrick
WABI
2010
Springer
160views Bioinformatics» more  WABI 2010»
9 years 6 months ago
Genomic Distance with DCJ and Indels
The double cut and join (DCJ) operation, introduced by Yancopoulos, Attie and Friedberg in 2005, allows one to represent most rearrangement events in genomes. However, a DCJ cannot...
Marília D. V. Braga, Eyla Willing, Jens Sto...
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