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ISMB
1993
13 years 5 months ago
A Multi-Level Description Scheme of Protein Conformation
Kentaro Onizuka, Stephen T. C. Wong, Masato Ishika...
ISMB
1993
13 years 5 months ago
Discovering Sequence Similarity by the Algorithmic Significance Method
The minimal-length encoding approach is applied to define concept of sequence similarity. Asequence is defined to be similar to another sequence or to a set of keywords if it can ...
Aleksandar Milosavljevic
ISMB
1993
13 years 5 months ago
Prediction of Primate Splice Junction Gene Sequences with a Cooperative Knowledge Acquisition System
Wepropose a cooperative conceptual modelling environment in which two agents interact : the machineand the humanexpert. Theformer is able to extract knowledge from data using a sy...
Engelbert Mephu Nguifo, Jean Sallantin
ISMB
1993
13 years 5 months ago
Identification of Localized and Distributed Bottlenecks in Metabolic Pathways
The usual thermodynamicevaluation, based solely on the Standard Gibbs Energyof reaction, does not take into account the permissible ranges of concentrations of metabolites, and it...
Michael L. Mavrovouniotis
ISMB
1993
13 years 5 months ago
MultiMap: An Expert System for Automated Genetic Linkage Mapping
Withthe advent of the HumanGenomeProject. the ability to rapidly construct comprehensiveand accuratelinkage mapsbasedongenetic markerdata fromfamily studies is an absolute necessi...
Tara Cox Matise, Mark Perlin, Aravinda Chakravarti
ISMB
1993
13 years 5 months ago
Design of an Object-Oriented Database for Reverse Genetics
Krys Kochut, Jonathan Arnold, John A. Miller, Walt...
ISMB
1993
13 years 5 months ago
Detection of Correlations in tRNA Sequences with Structural Implications
Using a flexible representation of biological sequences, we have performed a comparative analysis of 1208 known tRNA sequences. We believe we our technique is a more sensitive met...
Tod M. Klingler, Douglas L. Brutlag
ISMB
1993
13 years 5 months ago
Protein Sequencing Experiment Planning Using Analogy
Experiment design and execution is a central activity in the natural sciences. The SeqERsystem provides a general architecture for the integration of automated planning techniques...
Brian P. Kettler, Lindley Darden