Sciweavers

ALMOB
2008
127views more  ALMOB 2008»
13 years 4 months ago
HuMiTar: A sequence-based method for prediction of human microRNA targets
Background: MicroRNAs (miRs) are small noncoding RNAs that bind to complementary/partially complementary sites in the 3' untranslated regions of target genes to regulate prot...
Jishou Ruan, Hanzhe Chen, Lukasz A. Kurgan, Ke Che...
ALMOB
2008
92views more  ALMOB 2008»
13 years 4 months ago
Reconstructing phylogenies from noisy quartets in polynomial time with a high success probability
Background: In recent years, quartet-based phylogeny reconstruction methods have received considerable attentions in the computational biology community. Traditionally, the accura...
Gang Wu, Ming-Yang Kao, Guohui Lin, Jia-Huai You
ALMOB
2008
160views more  ALMOB 2008»
13 years 4 months ago
Syntenator: Multiple gene order alignments with a gene-specific scoring function
Background: Identification of homologous regions or conserved syntenies across genomes is one crucial step in comparative genomics. This task is usually performed by genome alignm...
Christian Rödelsperger, Christoph Dieterich
ALMOB
2008
93views more  ALMOB 2008»
13 years 4 months ago
A weighted average difference method for detecting differentially expressed genes from microarray data
Background: Identification of differentially expressed genes (DEGs) under different experimental conditions is an important task in many microarray studies. However, choosing whic...
Koji Kadota, Yuji Nakai, Kentaro Shimizu
ALMOB
2008
69views more  ALMOB 2008»
13 years 4 months ago
Learning from positive examples when the negative class is undetermined- microRNA gene identification
Background: The application of machine learning to classification problems that depend only on positive examples is gaining attention in the computational biology community. We an...
Malik Yousef, Segun Jung, Louise C. Showe, Michael...
ALMOB
2008
124views more  ALMOB 2008»
13 years 4 months ago
A scoring matrix approach to detecting miRNA target sites
Background: Experimental identification of microRNA (miRNA) targets is a difficult and time consuming process. As a consequence several computational prediction methods have been ...
Simon Moxon, Vincent Moulton, Jan T. Kim
ALMOB
2008
43views more  ALMOB 2008»
13 years 4 months ago
On the optimality of the neighbor-joining algorithm
Kord Eickmeyer, Peter Huggins, Lior Pachter, Rurik...
ALMOB
2008
95views more  ALMOB 2008»
13 years 4 months ago
A stitch in time: Efficient computation of genomic DNA melting bubbles
Background: It is of biological interest to make genome-wide predictions of the locations of DNA melting bubbles using statistical mechanics models. Computationally, this poses th...
Eivind Tøstesen
ALMOB
2008
112views more  ALMOB 2008»
13 years 4 months ago
Metabolite-based clustering and visualization of mass spectrometry data using one-dimensional self-organizing maps
Background: One of the goals of global metabolomic analysis is to identify metabolic markers that are hidden within a large background of data originating from high-throughput ana...
Peter Meinicke, Thomas Lingner, Alexander Kaever, ...
ALMOB
2008
82views more  ALMOB 2008»
13 years 4 months ago
Protein sequence and structure alignments within one framework
Background: Protein structure alignments are usually based on very different techniques to sequence alignments. We propose a method which treats sequence, structure and even combi...
Gundolf Schenk, Thomas Margraf, Andrew E. Torda