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NAR
2010
194views more  NAR 2010»
9 years 4 months ago
AltAnalyze and DomainGraph: analyzing and visualizing exon expression data
Alternative splicing is an important mechanism for increasing protein diversity. However, its functional effects are largely unknown. Here, we present our new software workflow co...
Dorothea Emig, Nathan Salomonis, Jan Baumbach, Tho...
NAR
2000
152views more  NAR 2000»
9 years 9 months ago
ASDB: database of alternatively spliced genes
Version 2.1 of ASDB (Alternative Splicing Data Base) contains 1922 protein and 2486 DNA sequences. The protein entries from SWISS-PROT are joined into clusters corresponding to al...
I. Dralyuk, Michael Brudno, Mikhail S. Gelfand, Ma...
BMCBI
2004
102views more  BMCBI 2004»
9 years 9 months ago
No statistical support for correlation between the positions of protein interaction sites and alternatively spliced regions
Background: Alternative splicing is an efficient mechanism for increasing the variety of functions fulfilled by proteins in a living cell. It has been previously demonstrated that...
Marc N. Offman, Ramil N. Nurtdinov, Mikhail S. Gel...
BMCBI
2004
121views more  BMCBI 2004»
9 years 9 months ago
DEDB: a database of Drosophila melanogaster exons in splicing graph form
Background: A wealth of quality genomic and mRNA/EST sequences in recent years has provided the data required for large-scale genome-wide analysis of alternative splicing. We have...
Bernett T. K. Lee, Tin Wee Tan, Shoba Ranganathan
BMCBI
2005
113views more  BMCBI 2005»
9 years 9 months ago
Alternative splicing and protein function
Background: Alternative splicing is a major mechanism of generating protein diversity in higher eukaryotes. Although at least half, and probably more, of mammalian genes are alter...
A. D. Neverov, Irena I. Artamonova, Ramil N. Nurtd...
NAR
2006
113views more  NAR 2006»
9 years 9 months ago
ASD: a bioinformatics resource on alternative splicing
Alternative splicing is an important regulatory mechanism of mammalian gene expression. The alternative splicing database (ASD) consortium is systematically collecting and annotat...
Stefan Stamm, Jean-Jack M. Riethoven, Vincent Le T...
CORR
2007
Springer
100views Education» more  CORR 2007»
9 years 9 months ago
Identifying statistical dependence in genomic sequences via mutual information estimates
Questions of understanding and quantifying the representation and amount of information in organisms have become a central part of biological research, as they potentially hold th...
H. M. Aktulga, I. Kontoyiannis, L. A. Lyznik, Luka...
BMCBI
2008
323views more  BMCBI 2008»
9 years 9 months ago
A compatible exon-exon junction database for the identification of exon skipping events using tandem mass spectrum data
Background: Alternative splicing is an important gene regulation mechanism. It is estimated that about 74% of multi-exon human genes have alternative splicing. High throughput tan...
Fan Mo, Xu Hong, Feng Gao, Lin Du, Jun Wang, Gilbe...
BMCBI
2008
162views more  BMCBI 2008»
9 years 9 months ago
Improved identification of conserved cassette exons using Bayesian networks
Background: Alternative splicing is a major contributor to the diversity of eukaryotic transcriptomes and proteomes. Currently, large scale detection of alternative splicing using...
Rileen Sinha, Michael Hiller, Rainer Pudimat, Ulri...
BMCBI
2008
132views more  BMCBI 2008»
9 years 9 months ago
Exon level integration of proteomics and microarray data
Background: Previous studies comparing quantitative proteomics and microarray data have generally found poor correspondence between the two. We hypothesised that this might in par...
Danny A. Bitton, Michal J. Okoniewski, Yvonne Conn...
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