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NAR
2011
222views Computer Vision» more  NAR 2011»
9 years 4 months ago
Effective - a database of predicted secreted bacterial proteins
Protein secretion is a key virulence mechanism of pathogenic and symbiotic bacteria, which makes the investigation of secreted proteins (‘effectors’) crucial for understanding...
Marc-André Jehl, Roland Arnold, Thomas Ratt...
NAR
2011
188views Computer Vision» more  NAR 2011»
9 years 4 months ago
ThYme: a database for thioester-active enzymes
The ThYme (Thioester-active enzYme; http://www .enzyme.cbirc.iastate.edu) database has been constructed to bring together amino acid sequences and 3D (tertiary) structures of all ...
David C. Cantu, Yingfei Chen, Matthew L. Lemons, P...
BMCBI
2010
98views more  BMCBI 2010»
10 years 1 months ago
Prediction of protein structural classes for low-homology sequences based on predicted secondary structure
Background: Prediction of protein structural classes (a, b, a + b and a/b) from amino acid sequences is of great importance, as it is beneficial to study protein function, regulat...
Jian-Yi Yang, Zhen-Ling Peng, Xin Chen
BIOCOMP
2009
10 years 2 months ago
Evidence against the Paradigm of Energy Minimization in Protein Design
Abstract-- Stating protein design as an energy minimization in the space of amino acid sequences and rotamer combinations is usual. In the current paper an evolutionary algorithm b...
Andrea Bazzoli, Andrea Tettamanzi
BIRD
2008
Springer
221views Bioinformatics» more  BIRD 2008»
10 years 3 months ago
Comparison of Exact String Matching Algorithms for Biological Sequences
Exact matching of single patterns in DNA and amino acid sequences is studied. We performed an extensive experimental comparison of algorithms presented in the literature. In additi...
Petri Kalsi, Hannu Peltola, Jorma Tarhio
AUSDM
2006
Springer
144views Data Mining» more  AUSDM 2006»
10 years 5 months ago
Mining Quantitative Association Rules in Protein Sequences
Abstract. Lot of research has gone into understanding the composition and nature of proteins, still many things remain to be understood satisfactorily. It is now generally believed...
Nitin Gupta, Nitin Mangal, Kamal Tiwari, Pabitra M...
CSB
2004
IEEE
115views Bioinformatics» more  CSB 2004»
10 years 5 months ago
PoPS: A Computational Tool for Modeling and Predicting Protease Specificity
Proteases play a fundamental role in the control of intra- and extracellular processes by binding and cleaving specific amino acid sequences. Identifying these targets is extremel...
Sarah E. Boyd, Maria J. García de la Banda,...
CSB
2003
IEEE
128views Bioinformatics» more  CSB 2003»
10 years 6 months ago
Degenerate Primer Design via Clustering
This paper describes a new strategy for designing degenerate primers for a given multiple alignment of amino acid sequences. Degenerate primers are useful for amplifying homologou...
Xintao Wei, David N. Kuhn, Giri Narasimhan
RECOMB
2005
Springer
11 years 1 months ago
Very Low Power to Detect Asymmetric Divergence of Duplicated Genes
Abstract. Asymmetric functional divergence of paralogues is a key aspect of the traditional model of evolution following duplication. If one gene continues to perform the ancestral...
Cathal Seoighe, Konrad Scheffler
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