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BIBE
2005
IEEE
9 years 3 months ago
A Multi-Level Approach to SCOP Fold Recognition
The classification of proteins based on their structure can play an important role in the deduction or discovery of protein function. However, the relatively low number of solved...
Keith Marsolo, Srinivasan Parthasarathy, Chris H. ...
BIBE
2005
IEEE
9 years 7 months ago
Using Data Mining Techniques to Learn Layouts of Flat-File Biological Datasets
One of the major problems in biological data integration is that many data sources are stored as flat-files, with a variety of different layouts. Integrating data from such sour...
Kaushik Sinha, Xuan Zhang, Ruoming Jin, Gagan Agra...
BIBE
2005
IEEE
9 years 7 months ago
Improved Phylogenetic Motif Detection Using Parsimony
We have recently demonstrated (La et al, Proteins, 58:2005) that sequence fragments approximating the overall familial phylogeny, called phylogenetic motifs (PMs), represent a pro...
Usman Roshan, Dennis R. Livesay, David La
BIBE
2005
IEEE
126views Bioinformatics» more  BIBE 2005»
9 years 7 months ago
Highly Scalable and Accurate Seeds for Subsequence Alignment
We propose a method for finding seeds for the local alignment of two nucleotide sequences. Our method uses randomized algorithms to find approximate seeds. We present a dynamic ...
Abhijit Pol, Tamer Kahveci
BIBE
2005
IEEE
9 years 7 months ago
GroupAdaBoost for Selecting Important Genes
Takashi Takenouchi, Masaru Ushijima, Shinto Eguchi
BIBE
2005
IEEE
154views Bioinformatics» more  BIBE 2005»
9 years 7 months ago
Effective Pre-Processing Strategies for Functional Clustering of a Protein-Protein Interactions Network
In this article we present novel preprocessing techniques, based on topological measures of the network, to identify clusters of proteins from Protein-protein interaction (PPI) ne...
Duygu Ucar, Srinivasan Parthasarathy, Sitaram Asur...
BIBE
2005
IEEE
9 years 7 months ago
Diagnostic Rules Induced by an Ensemble Method for Childhood Leukemia
We introduce a new ensemble method based on decision tree to discover significant and diversified rules for subtype classification of childhood acute lymphoblastic leukemia, a ...
Jinyan Li, Huiqing Liu, Ling Li
BIBE
2005
IEEE
126views Bioinformatics» more  BIBE 2005»
9 years 7 months ago
Suboptimal Alignments Improve the Detection of Weak Homologs in Sequence Database Searches
PSI-BLAST remains one of the popular tools for searching remote homologs in sequence databases. We recently demonstrated that hybrid alignment can function as the alignment core f...
Yuheng Li, Mario Lauria, Ralf Bundschuh
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