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PSB
2010
13 years 2 months ago
Writing and Compiling Code into Biochemistry
rmed at a conceptual level, in terms of abstract biochemical reactions
Adam Shea, Brian Fett, Marc D. Riedel, Keshab K. P...
BIOCOMP
2010
13 years 2 months ago
A Model Reduction Technique for Stochastic Biochemical Kinetics
Abstract-- Modeling the intermolecular reactions in a single cell is a critical problem in computational biology. Biochemical reaction systems often involve species in both low and...
Silvana Ilie, Ekaterina Kudashkina
JIB
2007
136views more  JIB 2007»
13 years 4 months ago
SABIO-RK: A data warehouse for biochemical reactions and their kinetics
Systems biology is an emerging field that aims at obtaining a system-level understanding of biological processes. The modelling and simulation of networks of biochemical reactions...
Olga Krebs, Martin Golebiewski, Renate Kania, Saqi...
BMCBI
2008
189views more  BMCBI 2008»
13 years 4 months ago
AnEnPi: identification and annotation of analogous enzymes
Background: Enzymes are responsible for the catalysis of the biochemical reactions in metabolic pathways. Analogous enzymes are able to catalyze the same reactions, but they prese...
Thomas D. Otto, Ana Carolina R. Guimarães, ...
KES
2004
Springer
13 years 9 months ago
Extracting Biochemical Reaction Kinetics from Time Series Data
We consider the problem of inferring kinetic mechanisms for biochemical reactions from time series data. Using a priori knowledge about the structure of chemical reaction kinetics ...
Edmund J. Crampin, Patrick E. McSharry, Santiago S...
ECAI
2004
Springer
13 years 10 months ago
Towards a Logical Analysis of Biochemical Reactions
We provide a logical model of biochemical reactions and show how hypothesis generation using weakest sufficient and strongest necessary conditions may be used to provide addition...
Patrick Doherty, Steve Kertes, Martin Magnusson, A...
ICCAD
2008
IEEE
133views Hardware» more  ICCAD 2008»
14 years 1 months ago
Module locking in biochemical synthesis
—We are developing a framework for computation with biochemical reactions with a focus on synthesizing specific logical functionality, a task analogous to technology-independent...
Brian Fett, Marc D. Riedel
DAC
2007
ACM
14 years 5 months ago
Synthesizing Stochasticity in Biochemical Systems
Randomness is inherent to biochemistry: at each instant, the sequence of reactions that fires is a matter of chance. Some biological systems exploit such randomness, choosing betw...
Brian Fett, Jehoshua Bruck, Marc D. Riedel