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BIODATAMINING
2008
130views more  BIODATAMINING 2008»
8 years 7 months ago
Uncovering mechanisms of transcriptional regulations by systematic mining of cis regulatory elements with gene expression profil
Background: Contrary to the traditional biology approach, where the expression patterns of a handful of genes are studied at a time, microarray experiments enable biologists to st...
Qicheng Ma, Gung-Wei Chirn, Joseph D. Szustakowski...
BIODATAMINING
2008
119views more  BIODATAMINING 2008»
8 years 7 months ago
A survey of visualization tools for biological network analysis
The analysis and interpretation of relationships between biological molecules, networks and concepts is becoming a major bottleneck in systems biology. Very often the pure amount ...
Georgios A. Pavlopoulos, Anna-Lynn Wegener, Reinha...
BIODATAMINING
2008
96views more  BIODATAMINING 2008»
8 years 7 months ago
Fast approximate hierarchical clustering using similarity heuristics
Background: Agglomerative hierarchical clustering (AHC) is a common unsupervised data analysis technique used in several biological applications. Standard AHC methods require that...
Meelis Kull, Jaak Vilo
BIODATAMINING
2008
117views more  BIODATAMINING 2008»
8 years 7 months ago
Search extension transforms Wiki into a relational system: A case for flavonoid metabolite database
Background: In computer science, database systems are based on the relational model founded by Edgar Codd in 1970. On the other hand, in the area of biology the word 'databas...
Masanori Arita, Kazuhiro Suwa
BIODATAMINING
2008
163views more  BIODATAMINING 2008»
8 years 7 months ago
Multivariate profiling of neurodegeneration-associated changes in a subcellular compartment of neurons via image processing
Background: Dysfunction in the endolysosome, a late endosomal to lysosomal degradative intracellular compartment, is an early hallmark of some neurodegenerative diseases, in parti...
Saravana K. Kumarasamy, Yunshi Wang, Vignesh Viswa...
BIODATAMINING
2008
135views more  BIODATAMINING 2008»
8 years 7 months ago
Fast Gene Ontology based clustering for microarray experiments
Background: Analysis of a microarray experiment often results in a list of hundreds of diseaseassociated genes. In order to suggest common biological processes and functions for t...
Kristian Ovaska, Marko Laakso, Sampsa Hautaniemi
BIODATAMINING
2008
85views more  BIODATAMINING 2008»
8 years 7 months ago
A review of estimation of distribution algorithms in bioinformatics
Evolutionary search algorithms have become an essential asset in the algorithmic toolbox for solving high-dimensional optimization problems in across a broad range of bioinformati...
Rubén Armañanzas, Iñaki Inza,...
BIODATAMINING
2008
120views more  BIODATAMINING 2008»
8 years 7 months ago
Filling the gap between biology and computer science
This editorial introduces BioData Mining, a new journal which publishes research articles related to advances in computational methods and techniques for the extraction of useful ...
Jesús S. Aguilar-Ruiz, Jason H. Moore, Mary...
BIODATAMINING
2008
140views more  BIODATAMINING 2008»
8 years 7 months ago
Modeling gene-by-environment interaction in comorbid depression with alcohol use disorders via an integrated bioinformatics appr
Background: Comorbidity of Major Depressive Disorder (depression) and Alcohol Use Disorders (AUD) is well documented. Depression, AUD, and the comorbidity of depression with AUD s...
Richard C. McEachin, Benjamin J. Keller, Erika F. ...
BIODATAMINING
2008
147views more  BIODATAMINING 2008»
8 years 7 months ago
Neural networks for genetic epidemiology: past, present, and future
During the past two decades, the field of human genetics has experienced an information explosion. The completion of the human genome project and the development of high throughpu...
Alison A. Motsinger-Reif, Marylyn D. Ritchie
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