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BIOINFORMATICS
2010
94views more  BIOINFORMATICS 2010»
13 years 4 months ago
Alignment-free local structural search by writhe decomposition
Degui Zhi, Maxim Shatsky, Steven E. Brenner
BIOINFORMATICS
2010
84views more  BIOINFORMATICS 2010»
13 years 4 months ago
partDSA: deletion/substitution/addition algorithm for partitioning the covariate space in prediction
The partDSA package (Molinaro, Lostritto, and Weston 2009) provides a novel recursive partitioning tool for prediction when numerous variables jointly affect the outcome. In such ...
Annette M. Molinaro, Karen Lostritto, Mark J. van ...
BIOINFORMATICS
2010
87views more  BIOINFORMATICS 2010»
13 years 4 months ago
Improving protein secondary structure prediction using a simple k-mer model
Motivation: Existing methods for protein sequence analysis are generally firstorder and inherently assume that each position is independent. We develop a general framework for int...
Martin Madera, Ryan Calmus, Grant Thiltgen, Kevin ...
BIOINFORMATICS
2010
84views more  BIOINFORMATICS 2010»
13 years 4 months ago
Robust biomarker identification for cancer diagnosis with ensemble feature selection methods
Thomas Abeel, Thibault Helleputte, Yves Van de Pee...
BIOINFORMATICS
2010
170views more  BIOINFORMATICS 2010»
13 years 4 months ago
Joint estimation of DNA copy number from multiple platforms
DNA copy number variants (CNV) are gains and losses of segments of chromosomes, and comprise an important class of genetic variation. Recently, various microarray hybridization ba...
Nancy R. Zhang, Yasin Senbabaoglu, Jun Z. Li
BIOINFORMATICS
2010
67views more  BIOINFORMATICS 2010»
13 years 4 months ago
Target prediction and a statistical sampling algorithm for RNA-RNA interaction
Fenix W. D. Huang, Jing Qin, Christian M. Reidys, ...
BIOINFORMATICS
2010
116views more  BIOINFORMATICS 2010»
13 years 4 months ago
A principal skeleton algorithm for standardizing confocal images of fruit fly nervous systems
Motivation: The fruit fly (Drosophila melanogaster) is a commonly used model organism in biology. We are currently building a 3D digital atlas of the fruit fly larval nervous syst...
Lei Qu, Hanchuan Peng
BIOINFORMATICS
2010
94views more  BIOINFORMATICS 2010»
13 years 4 months ago
Tmod: toolbox of motif discovery
Hanchang Sun, Yuan Yuan, Yibo Wu, Hui Liu, Jun S. ...
BIOINFORMATICS
2010
109views more  BIOINFORMATICS 2010»
13 years 4 months ago
Phylogenetic networks do not need to be complex: using fewer reticulations to represent conflicting clusters
Phylogenetic trees are widely used to display estimates of how groups of species evolved. Each phylogenetic tree can be seen as a collection of clusters, subgroups of the species ...
Leo van Iersel, Steven Kelk, Regula Rupp, Daniel H...
BIOINFORMATICS
2010
70views more  BIOINFORMATICS 2010»
13 years 4 months ago
Reporting bias when using real data sets to analyze classification performance
Mohammadmahdi R. Yousefi, Jianping Hua, Chao Sima,...