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BMCBI
2007
135views more  BMCBI 2007»
13 years 4 months ago
LIMPIC: a computational method for the separation of protein MALDI-TOF-MS signals from noise
Background: Mass spectrometry protein profiling is a promising tool for biomarker discovery in clinical proteomics. However, the development of a reliable approach for the separat...
Dante Mantini, Francesca Petrucci, Damiana Pierago...
BMCBI
2010
135views more  BMCBI 2010»
13 years 4 months ago
Quadratic variance models for adaptively preprocessing SELDI-TOF mass spectrometry data
Background: Surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI) is a proteomics tool for biomarker discovery and other high throughput applicatio...
Vincent A. Emanuele II, Brian M. Gurbaxani
BMCBI
2010
119views more  BMCBI 2010»
13 years 4 months ago
Coherent pipeline for biomarker discovery using mass spectrometry and bioinformatics
Background: Robust biomarkers are needed to improve microbial identification and diagnostics. Proteomics methods based on mass spectrometry can be used for the discovery of novel ...
Ali Al-Shahib, Raju Misra, Nadia Ahmod, Min Fang, ...
DILS
2007
Springer
13 years 6 months ago
A High-Throughput Bioinformatics Platform for Mass Spectrometry-Based Proteomics
The success of mass spectrometry-based proteomics in emerging applications such as biomarker discovery and clinical diagnostics, is predicated substantially on its ability to achie...
Thodoros Topaloglou, Moyez Dharsee, Rob M. Ewing, ...
GECCO
2005
Springer
218views Optimization» more  GECCO 2005»
13 years 10 months ago
Particle swarm optimization for analysis of mass spectral serum profiles
Serum profiling using mass spectrometry is an emerging technology with a great potential to provide biomarkers for complex diseases such as cancer. However, protein profiles obtai...
Habtom W. Ressom, Rency S. Varghese, Daniel Saha, ...