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BMCBI
2004
114views more  BMCBI 2004»
8 years 11 months ago
Extending the mutual information measure to rank inferred literature relationships
Background: Within the peer-reviewed literature, associations between two things are not always recognized until commonalities between them become apparent. These commonalities ca...
Jonathan D. Wren
BMCBI
2004
150views more  BMCBI 2004»
8 years 11 months ago
Inter-residue distances derived from fold contact propensities correlate with evolutionary substitution costs
Background: The wealth of information on protein structure has led to a variety of statistical analyses of the role played by individual amino acid types in the protein fold. In p...
Gareth Williams, Patrick Doherty
BMCBI
2004
144views more  BMCBI 2004»
8 years 11 months ago
PASBio: predicate-argument structures for event extraction in molecular biology
Background: The exploitation of information extraction (IE), a technology aiming to provide instances of structured representations from free-form text, has been rapidly growing w...
Tuangthong Wattarujeekrit, Parantu K. Shah, Nigel ...
BMCBI
2004
70views more  BMCBI 2004»
8 years 11 months ago
M-CGH: Analysing microarray-based CGH experiments
Junbai Wang, Leonardo A. Meza-Zepeda, Stine H. Kre...
BMCBI
2004
150views more  BMCBI 2004»
8 years 11 months ago
SS-Wrapper: a package of wrapper applications for similarity searches on Linux clusters
Background: Large-scale sequence comparison is a powerful tool for biological inference in modern molecular biology. Comparing new sequences to those in annotated databases is a u...
Chunlin Wang, Elliot J. Lefkowitz
BMCBI
2004
153views more  BMCBI 2004»
8 years 11 months ago
Computational protein biomarker prediction: a case study for prostate cancer
Background: Recent technological advances in mass spectrometry pose challenges in computational mathematics and statistics to process the mass spectral data into predictive models...
Michael Wagner, Dayanand N. Naik, Alex Pothen, Sri...
BMCBI
2004
252views more  BMCBI 2004»
8 years 11 months ago
Applying Support Vector Machines for Gene ontology based gene function prediction
Background: The current progress in sequencing projects calls for rapid, reliable and accurate function assignments of gene products. A variety of methods has been designed to ann...
Arunachalam Vinayagam, Rainer König, Jutta Mo...
BMCBI
2004
77views more  BMCBI 2004»
8 years 11 months ago
A structural study for the optimisation of functional motifs encoded in protein sequences
Background: A large number of PROSITE patterns select false positives and/or miss known true positives. It is possible that
Allegra Via, Manuela Helmer-Citterich
BMCBI
2004
181views more  BMCBI 2004»
8 years 11 months ago
Iterative class discovery and feature selection using Minimal Spanning Trees
Background: Clustering is one of the most commonly used methods for discovering hidden structure in microarray gene expression data. Most current methods for clustering samples ar...
Sudhir Varma, Richard Simon
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