BMCBI
2004
13 years 4 months ago
2004
Background: Subcellular localization of a new protein sequence is very important and fruitful for understanding its function. As the number of new genomes has dramatically increas...
BMCBI
2004
13 years 4 months ago
2004
Background: A detailed understanding of an RNA's correct secondary and tertiary structure is crucial to understanding its function and mechanism in the cell. Free energy mini...
BMCBI
2004
13 years 4 months ago
2004
Background: Because loops connect regular secondary structures, analysis of the former depends directly on the definition of the latter. The numerous assignment methods, however, ...
BMCBI
2004
13 years 4 months ago
2004
Background: Transcriptional regulation is a key mechanism in the functioning of the cell, and is mostly effected through transcription factors binding to specific recognition moti...
BMCBI
2004
13 years 4 months ago
2004
Background: Alignment and comparison of related genome sequences is a powerful method to identify regions likely to contain functional elements. Such analyses are data intensive, ...
BMCBI
2004
13 years 4 months ago
2004
Background: Existing sequence alignment algorithms assume that similarities between DNA or amino acid sequences are linearly ordered. That is, stretches of similar nucleotides or ...
BMCBI
2004
13 years 4 months ago
2004
Background: Microarrays have emerged as the preferred platform for high throughput gene expression analysis. Cross-hybridization among genes with high sequence similarities can be...
BMCBI
2004
13 years 4 months ago
2004
Background: It is well known that different species have different protein domain repertoires, and indeed that some protein domains are kingdom specific. This information has not ...
BMCBI
2004
13 years 4 months ago
2004
Background: The proliferation of structural and functional studies of RNA has revealed an increasing range of RNA's structural repertoire. Toward the objective of systematic ...
BMCBI
2004
13 years 4 months ago
2004