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BMCBI
2004
76views more  BMCBI 2004»
9 years 1 months ago
An imaging system for standardized quantitative analysis of C. elegans behavior
Zhaoyang Feng, Christopher J. Cronin, John H. Witt...
BMCBI
2004
174views more  BMCBI 2004»
9 years 1 months ago
SeeGH - A software tool for visualization of whole genome array comparative genomic hybridization data
Background: Array comparative genomic hybridization (CGH) is a technique which detects copy number differences in DNA segments. Complete sequencing of the human genome and the dev...
Bryan Chi, Ronald J. deLeeuw, Bradley P. Coe, Calu...
BMCBI
2004
174views more  BMCBI 2004»
9 years 1 months ago
Implications for domain fusion protein-protein interactions based on structural information
Background: Several in silico methods exist that were developed to predict protein interactions from the copious amount of genomic and proteomic data. One of these methods is Doma...
Jer-Ming Chia, Prasanna R. Kolatkar
BMCBI
2004
128views more  BMCBI 2004»
9 years 1 months ago
Structural characterization of genomes by large scale sequence-structure threading: application of reliability analysis in struc
Background: We establish that the occurrence of protein folds among genomes can be accurately described with a Weibull function. Systems which exhibit Weibull character can be int...
Artem Cherkasov, Shannan J. Ho Sui, Robert C. Brun...
BMCBI
2004
120views more  BMCBI 2004»
9 years 1 months ago
An approach to large scale identification of non-obvious structural similarities between proteins
Background: A new sequence independent bioinformatics approach allowing genome-wide search for proteins with similar three dimensional structures has been developed. By utilizing ...
Artem Cherkasov, Steven J. M. Jones
BMCBI
2004
75views more  BMCBI 2004»
9 years 1 months ago
Structural characterization of genomes by large scale sequence-structure threading
Background: Using sequence-structure threading we have conducted structural characterization of complete proteomes of 37 archaeal, bacterial and eukaryotic organisms (including wo...
Artem Cherkasov, Steven J. M. Jones
BMCBI
2004
101views more  BMCBI 2004»
9 years 1 months ago
A database for G proteins and their interaction with GPCRs
Background: G protein-coupled receptors (GPCRs) transduce signals from extracellular space into the cell, through their interaction with G proteins, which act as switches forming ...
Antigoni L. Elefsinioti, Pantelis G. Bagos, Ioanni...
BMCBI
2004
94views more  BMCBI 2004»
9 years 1 months ago
GASP: Gapped Ancestral Sequence Prediction for proteins
Background: The prediction of ancestral protein sequences from multiple sequence alignments is useful for many bioinformatics analyses. Predicting ancestral sequences is not a sim...
Richard J. Edwards, Denis C. Shields
BMCBI
2004
196views more  BMCBI 2004»
9 years 1 months ago
MUSCLE: a multiple sequence alignment method with reduced time and space complexity
Background: In a previous paper, we introduced MUSCLE, a new program for creating multiple alignments of protein sequences, giving a brief summary of the algorithm and showing MUS...
Robert C. Edgar
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