BMCBI
2004
13 years 4 months ago
2004
Background: The discovery of cis-regulatory modules in metazoan genomes is crucial for understanding the connection between genes and organism diversity. It is important to quanti...
BMCBI
2004
13 years 4 months ago
2004
Background: This paper addresses the problem of discovering transcription factor binding sites in heterogeneous sequence data, which includes regulatory sequences of one or more g...
BMCBI
2004
13 years 4 months ago
2004
BMCBI
2004
13 years 4 months ago
2004
Background: We present Pegasys
BMCBI
2004
13 years 4 months ago
2004
Background: Protein-protein interactions play a critical role in protein function. Completion of many genomes is being followed rapidly by major efforts to identify interacting pr...
BMCBI
2004
13 years 4 months ago
2004
Background: Motivated by a biomedical database set up by our group, we aimed to develop a generic database front-end with embedded knowledge discovery and analysis features. A maj...
BMCBI
2004
13 years 4 months ago
2004
Background: Profile Hidden Markov Models (pHMMs) are a widely used tool for protein family research. Up to now, however, there exists no method to visualize all of their central a...
BMCBI
2004
13 years 4 months ago
2004
Background: Parallel computing is frequently used to speed up computationally expensive tasks in Bioinformatics. Results: Herein, a parallel version of the multi-alignment program...
BMCBI
2004
13 years 4 months ago
2004
Background: The Split ends (Spen) family are large proteins characterised by N-terminal RNA recognition motifs (RRMs) and a conserved SPOC (Spen paralog and ortholog C-terminal) d...
BMCBI
2004
13 years 4 months ago
2004
Background: A number of completely sequenced eukaryotic genome data are available in the public domain. Eukaryotic genes are either 'intron containing' or 'intronle...