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BMCBI
2004
123views more  BMCBI 2004»
8 years 11 months ago
Interaction profile-based protein classification of death domain
Background: The increasing number of protein sequences and 3D structure obtained from genomic initiatives is leading many of us to focus on proteomics, and to dedicate our experim...
Drew Lett, Michael Hsing, Frederic Pio
BMCBI
2004
149views more  BMCBI 2004»
8 years 11 months ago
MiCoViTo: a tool for gene-centric comparison and visualization of yeast transcriptome states
Background: Information obtained by DNA microarray technology gives a rough snapshot of the transcriptome state, i.e., the expression level of all the genes expressed in a cell po...
Gaëlle Lelandais, Philippe Marc, Pierre Vince...
BMCBI
2004
121views more  BMCBI 2004»
8 years 11 months ago
DEDB: a database of Drosophila melanogaster exons in splicing graph form
Background: A wealth of quality genomic and mRNA/EST sequences in recent years has provided the data required for large-scale genome-wide analysis of alternative splicing. We have...
Bernett T. K. Lee, Tin Wee Tan, Shoba Ranganathan
BMCBI
2004
106views more  BMCBI 2004»
8 years 11 months ago
ESTIMA, a tool for EST management in a multi-project environment
Background: Single-pass, partial sequencing of complementary DNA (cDNA) libraries generates thousands of chromatograms that are processed into high quality expressed sequence tags...
Charu G. Kumar, Richard LeDuc, George Gong, Levan ...
BMCBI
2004
96views more  BMCBI 2004»
8 years 11 months ago
Gene finding in novel genomes
Background: Computational gene prediction continues to be an important problem, especially for genomes with little experimental data. Results: I introduce the SNAP gene finder whi...
Ian Korf
BMCBI
2004
161views more  BMCBI 2004»
8 years 11 months ago
Three-parameter lognormal distribution ubiquitously found in cDNA microarray data and its application to parametric data treatme
Background: To cancel experimental variations, microarray data must be normalized prior to analysis. Where an appropriate model for statistical data distribution is available, a p...
Tomokazu Konishi
BMCBI
2004
131views more  BMCBI 2004»
8 years 11 months ago
A web services choreography scenario for interoperating bioinformatics applications
Background: Very often genome-wide data analysis requires the interoperation of multiple databases and analytic tools. A large number of genome databases and bioinformatics applic...
Remko de Knikker, Youjun Guo, Jin-long Li, Albert ...
BMCBI
2004
64views more  BMCBI 2004»
8 years 11 months ago
Reuse of imputed data in microarray analysis increases imputation efficiency
Ki-Yeol Kim, Byoung-Jin Kim, Gwan-Su Yi
BMCBI
2004
88views more  BMCBI 2004»
8 years 11 months ago
Coronavirus 3CLpro proteinase cleavage sites: Possible relevance to SARS virus pathology
Background: Despite the passing of more than a year since the first outbreak of Severe Acute Respiratory Syndrome (SARS), efficient counter-measures are still few and many believe...
Lars Kiemer, Ole Lund, Søren Brunak, Nikola...
BMCBI
2004
90views more  BMCBI 2004»
8 years 11 months ago
Haplotype frequency estimation error analysis in the presence of missing genotype data
Background: Increasingly researchers are turning to the use of haplotype analysis as a tool in population studies, the investigation of linkage disequilibrium, and candidate gene ...
Enda D. Kelly, Fabian Sievers, Ross McManus
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