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BMCBI
2005
114views more  BMCBI 2005»
8 years 10 months ago
A new decoding algorithm for hidden Markov models improves the prediction of the topology of all-beta membrane proteins
Background: Structure prediction of membrane proteins is still a challenging computational problem. Hidden Markov models (HMM) have been successfully applied to the problem of pre...
Piero Fariselli, Pier Luigi Martelli, Rita Casadio
BMCBI
2005
90views more  BMCBI 2005»
8 years 10 months ago
Text Detective: a rule-based system for gene annotation in biomedical texts
Background: The identification of mentions of gene or gene products in biomedical texts is a critical step in the development of text mining applications in biosciences. The compl...
Javier Tamames
BMCBI
2005
117views more  BMCBI 2005»
8 years 10 months ago
HmtDB, a Human Mitochondrial Genomic Resource Based on Variability Studies Supporting Population Genetics and Biomedical Researc
Background: Population genetics studies based on the analysis of mtDNA and mitochondrial disease studies have produced a huge quantity of sequence data and related information. Th...
Marcella Attimonelli, Matteo Accetturo, Monica San...
BMCBI
2005
106views more  BMCBI 2005»
8 years 10 months ago
ESTree db: a Tool for Peach Functional Genomics
Background: The ESTree db http://www.itb.cnr.it/estree/ represents a collection of Prunus persica expressed sequenced tags (ESTs) and is intended as a resource for peach functiona...
Barbara Lazzari, Andrea Caprera, Alberto Vecchiett...
BMCBI
2005
131views more  BMCBI 2005»
8 years 10 months ago
Regularized Least Squares Cancer Classifiers from DNA microarray data
Background: The advent of the technology of DNA microarrays constitutes an epochal change in the classification and discovery of different types of cancer because the information ...
Nicola Ancona, Rosalia Maglietta, Annarita D'Addab...
BMCBI
2005
73views more  BMCBI 2005»
8 years 10 months ago
Exploring the boundaries: gene and protein identification in biomedical text
We present a maximum-entropy based system incorporating a diverse set of features for identifying genes and proteins in biomedical s. This system was entered in the BioCreative co...
Jenny Rose Finkel, Shipra Dingare, Christopher D. ...
BMCBI
2005
246views more  BMCBI 2005»
8 years 10 months ago
ParPEST: a pipeline for EST data analysis based on parallel computing
Background: Expressed Sequence Tags (ESTs) are short and error-prone DNA sequences generated from the 5' and 3' ends of randomly selected cDNA clones. They provide an im...
Nunzio D'Agostino, Mario Aversano, Maria Luisa Chi...
BMCBI
2005
157views more  BMCBI 2005»
8 years 10 months ago
Decision Forest Analysis of 61 Single Nucleotide Polymorphisms in a Case-Control Study of Esophageal Cancer; a novel method
Background: Systematic evaluation and study of single nucleotide polymorphisms (SNPs) made possible by high throughput genotyping technologies and bioinformatics promises to provi...
Qian Xie, Luke D. Ratnasinghe, Huixiao Hong, Roger...
BMCBI
2005
134views more  BMCBI 2005»
8 years 10 months ago
Inherited disorder phenotypes: controlled annotation and statistical analysis for knowledge mining from gene lists
Background: Analysis of inherited diseases and their associated phenotypes is of great importance to gain knowledge of underlying genetic interactions and could ultimately give cl...
Marco Masseroli, Osvaldo Galati, Mauro Manzotti, K...
BMCBI
2005
189views more  BMCBI 2005»
8 years 10 months ago
A sentence sliding window approach to extract protein annotations from biomedical articles
Background: Within the emerging field of text mining and statistical natural language processing (NLP) applied to biomedical articles, a broad variety of techniques have been deve...
Martin Krallinger, Maria Padron, Alfonso Valencia
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