BMCBI
2005
13 years 4 months ago
2005
Background: Exhaustive methods of sequence alignment are accurate but slow, whereas heuristic approaches run quickly, but their complexity makes them more difficult to implement. ...
BMCBI
2005
13 years 4 months ago
2005
Background: The protein folding problem is a fundamental problems in computational molecular biology and biochemical physics. Various optimisation methods have been applied to for...
BMCBI
2005
13 years 4 months ago
2005
Background: To standardize gene product descriptions, a formal vocabulary defined as the Gene Ontology (GO) has been developed. GO terms have been categorized into biological proc...
BMCBI
2005
13 years 4 months ago
2005
Background: A critical step in processing oligonucleotide microarray data is combining the information in multiple probes to produce a single number that best captures the express...
BMCBI
2005
13 years 4 months ago
2005
Background: Tissue microarray (TMA) technology has been developed to facilitate large, genome-scale molecular pathology studies. This technique provides a high-throughput method f...
BMCBI
2005
13 years 4 months ago
2005
Background: Cells react to changing intra- and extracellular signals by dynamically modulating complex biochemical networks. Cellular responses to extracellular signals lead to ch...
BMCBI
2005
13 years 4 months ago
2005
BMCBI
2005
13 years 4 months ago
2005
BMCBI
2005
13 years 4 months ago
2005
Background: We present a biological data warehouse called Atlas that locally stores and integrates biological sequences, molecular interactions, homology information, functional a...
BMCBI
2005
13 years 4 months ago
2005
Background: G- Protein coupled receptors (GPCRs) comprise the largest group of eukaryotic cell surface receptors with great pharmacological interest. A broad range of native ligan...