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BMCBI
2005
77views more  BMCBI 2005»
13 years 4 months ago
Structural comparison of metabolic networks in selected single cell organisms
Background: There has been tremendous interest in the study of biological network structure. An array of measurements has been conceived to assess the topological properties of th...
Dongxiao Zhu, Zhaohui S. Qin
BMCBI
2005
75views more  BMCBI 2005»
13 years 4 months ago
Phylogenetic detection of conserved gene clusters in microbial genomes
Yu Zheng, Brian P. Anton, Richard J. Roberts, Simo...
BMCBI
2005
169views more  BMCBI 2005»
13 years 4 months ago
An adaptive method for cDNA microarray normalization
Background: Normalization is a critical step in analysis of gene expression profiles. For duallabeled arrays, global normalization assumes that the majority of the genes on the ar...
Yingdong Zhao, Ming-Chung Li, Richard Simon
BMCBI
2005
97views more  BMCBI 2005»
13 years 4 months ago
Comparative mapping of sequence-based and structure-based protein domains
Background: Protein domains have long been an ill-defined concept in biology. They are generally described as autonomous folding units with evolutionary and functional independenc...
Ya Zhang, John-Marc Chandonia, Chris H. Q. Ding, S...
BMCBI
2005
250views more  BMCBI 2005»
13 years 4 months ago
FiatFlux - a software for metabolic flux analysis from 13C-glucose experiments
Background: Quantitative knowledge of intracellular fluxes is important for a comprehensive characterization of metabolic networks and their functional operation. In contrast to d...
Nicola Zamboni, Eliane Fischer, Uwe Sauer
BMCBI
2005
82views more  BMCBI 2005»
13 years 4 months ago
Sources of variation in Affymetrix microarray experiments
Stanislav O. Zakharkin, Kyoungmi Kim, Tapan Mehta,...
BMCBI
2005
77views more  BMCBI 2005»
13 years 4 months ago
The Gene Set Builder: collation, curation, and distribution of sets of genes
Background: In bioinformatics and genomics, there are many applications designed to investigate the common properties for a set of genes. Often, these multi-gene analysis tools at...
Dimas Yusuf, Jonathan S. Lim, Wyeth W. Wasserman
BMCBI
2005
122views more  BMCBI 2005»
13 years 4 months ago
A microarray data-based semi-kinetic method for predicting quantitative dynamics of genetic networks
Background: Elucidating the dynamic behaviour of genetic regulatory networks is one of the most significant challenges in systems biology. However, conventional quantitative predi...
Katsuyuki Yugi, Yoichi Nakayama, Shigen Kojima, To...
BMCBI
2005
116views more  BMCBI 2005»
13 years 4 months ago
A computational approach for identifying pathogenicity islands in prokaryotic genomes
Background: Pathogenicity islands (PAIs), distinct genomic segments of pathogens encoding virulence factors, represent a subgroup of genomic islands (GIs) that have been acquired ...
Sung Ho Yoon, Cheol-Goo Hur, Ho-Young Kang, Yeoun ...