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BMCBI
2010
189views more  BMCBI 2010»
8 years 6 months ago
solQTL: a tool for QTL analysis, visualization and linking to genomes at SGN database
Background: A common approach to understanding the genetic basis of complex traits is through identification of associated quantitative trait loci (QTL). Fine mapping QTLs require...
Isaak Y. Tecle, Naama Menda, Robert M. Buels, Esth...
BMCBI
2008
181views more  BMCBI 2008»
8 years 6 months ago
Assessing batch effects of genotype calling algorithm BRLMM for the Affymetrix GeneChip Human Mapping 500 K array set using 270
Background: Genome-wide association studies (GWAS) aim to identify genetic variants (usually single nucleotide polymorphisms [SNPs]) across the entire human genome that are associ...
Huixiao Hong, Zhenqiang Su, Weigong Ge, Leming M. ...
BMCBI
2008
149views more  BMCBI 2008»
8 years 6 months ago
MD-SeeGH: a platform for integrative analysis of multi-dimensional genomic data
Background: Recent advances in global genomic profiling methodologies have enabled multidimensional characterization of biological systems. Complete analysis of these genomic prof...
Bryan Chi, Ronald J. deLeeuw, Bradley P. Coe, Raym...
BMCBI
2008
214views more  BMCBI 2008»
8 years 6 months ago
Enhanced Bayesian modelling in BAPS software for learning genetic structures of populations
Background: During the most recent decade many Bayesian statistical models and software for answering questions related to the genetic structure underlying population samples have...
Jukka Corander, Pekka Marttinen, Jukka Siré...
BMCBI
2008
166views more  BMCBI 2008»
8 years 6 months ago
QuantPrime - a flexible tool for reliable high-throughput primer design for quantitative PCR
Background: Medium- to large-scale expression profiling using quantitative polymerase chain reaction (qPCR) assays are becoming increasingly important in genomics research. A majo...
Samuel Arvidsson, Miroslaw Kwasniewski, Diego Maur...
BMCBI
2008
191views more  BMCBI 2008»
8 years 6 months ago
BatchPrimer3: A high throughput web application for PCR and sequencing primer design
Background: Microsatellite (simple sequence repeat
Frank M. You, Naxin Huo, Yong Qiang Gu, Ming-Cheng...
BMCBI
2010
110views more  BMCBI 2010»
8 years 7 months ago
Improvements to previous algorithms to predict gene structure and isoform concentrations using Affymetrix Exon arrays
Background: Exon arrays provide a way to measure the expression of different isoforms of genes in an organism. Most of the procedures to deal with these arrays are focused on gene...
Miguel A. Anton, Ander Aramburu, Angel Rubio
BMCBI
2010
153views more  BMCBI 2010»
8 years 7 months ago
DiffCoEx: a simple and sensitive method to find differentially coexpressed gene modules
Background: Large microarray datasets have enabled gene regulation to be studied through coexpression analysis. While numerous methods have been developed for identifying differen...
Bruno M. Tesson, Rainer Breitling, Ritsert C. Jans...
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