BMCBI
2010
13 years 2 months ago
2010
Background: A common approach to understanding the genetic basis of complex traits is through identification of associated quantitative trait loci (QTL). Fine mapping QTLs require...
BMCBI
2008
13 years 3 months ago
2008
Background: Genome-wide association studies (GWAS) aim to identify genetic variants (usually single nucleotide polymorphisms [SNPs]) across the entire human genome that are associ...
BMCBI
2008
13 years 3 months ago
2008
Background: Recent advances in global genomic profiling methodologies have enabled multidimensional characterization of biological systems. Complete analysis of these genomic prof...
BMCBI
2008
13 years 3 months ago
2008
Background: During the most recent decade many Bayesian statistical models and software for answering questions related to the genetic structure underlying population samples have...
BMCBI
2008
13 years 3 months ago
2008
Background: Medium- to large-scale expression profiling using quantitative polymerase chain reaction (qPCR) assays are becoming increasingly important in genomics research. A majo...
BMCBI
2008
13 years 3 months ago
2008
Background: Microsatellite (simple sequence repeat
BMCBI
2010
13 years 3 months ago
2010
BMCBI
2010
13 years 3 months ago
2010
Background: Exon arrays provide a way to measure the expression of different isoforms of genes in an organism. Most of the procedures to deal with these arrays are focused on gene...
BMCBI
2010
13 years 3 months ago
2010
Background: Large microarray datasets have enabled gene regulation to be studied through coexpression analysis. While numerous methods have been developed for identifying differen...
