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BMCBI
2007
154views more  BMCBI 2007»
13 years 4 months ago
Inferring biological networks with output kernel trees
Background: Elucidating biological networks between proteins appears nowadays as one of the most important challenges in systems biology. Computational approaches to this problem ...
Pierre Geurts, Nizar Touleimat, Marie Dutreix, Flo...
BMCBI
2007
103views more  BMCBI 2007»
13 years 4 months ago
Nanopore-based kinetics analysis of individual antibody-channel and antibody-antigen interactions
Background: The UNO/RIC Nanopore Detector provides a new way to study the binding and conformational changes of individual antibodies. Many critical questions regarding antibody f...
Stephen Winters-Hilt, Eric Morales, Iftekhar Amin,...
BMCBI
2007
83views more  BMCBI 2007»
13 years 4 months ago
ChIP-on-chip significance analysis reveals ubiquitous transcription factor binding
Adam A. Margolin, Teresa Palomero, Adolfo A. Ferra...
BMCBI
2007
167views more  BMCBI 2007»
13 years 4 months ago
A stochastic differential equation model for transcriptional regulatory networks
Background: This work explores the quantitative characteristics of the local transcriptional regulatory network based on the availability of time dependent gene expression data se...
Adriana Climescu-Haulica, Michelle D. Quirk
BMCBI
2007
174views more  BMCBI 2007»
13 years 4 months ago
ESTuber db: an online database for Tuber borchii EST sequences
Background: The ESTuber database (http://www.itb.cnr.it/estuber) includes 3,271 Tuber borchii expressed sequence tags (EST). The dataset consists of 2,389 sequences from an in-hou...
Barbara Lazzari, Andrea Caprera, Cristian Cosentin...
BMCBI
2007
116views more  BMCBI 2007»
13 years 4 months ago
Clustering protein environments for function prediction: finding PROSITE motifs in 3D
Background: Structural genomics initiatives are producing increasing numbers of threedimensional (3D) structures for which there is little functional information. Structure-based ...
Sungroh Yoon, Jessica C. Ebert, Eui-Young Chung, G...
BMCBI
2007
123views more  BMCBI 2007»
13 years 4 months ago
GO for gene documents
Annotating genes and their products with Gene Ontology codes is an important area of research. One approach for doing this is to use the information available about these genes in...
Padmini Srinivasan, Xin Ying Qiu
BMCBI
2007
122views more  BMCBI 2007»
13 years 4 months ago
Dissecting complex transcriptional responses using pathway-level scores based on prior information
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
Harmen J. Bussemaker, Lucas D. Ward, André ...
BMCBI
2007
116views more  BMCBI 2007»
13 years 4 months ago
Cloning, analysis and functional annotation of expressed sequence tags from the Earthworm Eisenia fetida
Background: Eisenia fetida, commonly known as red wiggler or compost worm, belongs to the Lumbricidae family of the Annelida phylum. Little is known about its genome sequence alth...
Mehdi Pirooznia, Ping Gong, Xin Guan, Laura S. Ino...
BMCBI
2007
144views more  BMCBI 2007»
13 years 4 months ago
Automatic delineation of malignancy in histopathological head and neck slides
Background: Histopathology, which is one of the most important routines of all laboratory procedures used in pathology, is decisive for the diagnosis of cancer. Experienced histop...
Mutlu Mete, Xiaowei Xu, Chun-Yang Fan, Gal Shafirs...