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BMCBI
2007
140views more  BMCBI 2007»
13 years 3 months ago
Evaluation of high-throughput functional categorization of human disease genes
Background: Biological data that are well-organized by an ontology, such as Gene Ontology, enables high-throughput availability of the semantic web. It can also be used to facilit...
James L. Chen, Yang Liu, Lee T. Sam, Jianrong Li, ...
BMCBI
2007
48views more  BMCBI 2007»
13 years 3 months ago
NIPS workshop on New Problems and Methods in Computational Biology
Gal Chechik, Christina S. Leslie, William Stafford...
BMCBI
2007
107views more  BMCBI 2007»
13 years 3 months ago
A computational approach for detecting peptidases and their specific inhibitors at the genome level
Background: Peptidases are proteolytic enzymes responsible for fundamental cellular activities in all organisms. Apparently about 2–5% of the genes encode for peptidases, irresp...
Lisa Bartoli, Remo Calabrese, Piero Fariselli, Dam...
BMCBI
2007
103views more  BMCBI 2007»
13 years 3 months ago
Cross platform microarray analysis for robust identification of differentially expressed genes
Roberta Bosotti, Giuseppe Locatelli, Sandra Healy,...
BMCBI
2007
148views more  BMCBI 2007»
13 years 3 months ago
p53FamTaG: a database resource of human p53, p63 and p73 direct target genes combining in silico prediction and microarray data
Background: The p53 gene family consists of the three genes p53, p63 and p73, which have polyhedral non-overlapping functions in pivotal cellular processes such as DNA synthesis a...
Elisabetta Sbisà, Domenico Catalano, Giorgi...
BMCBI
2007
128views more  BMCBI 2007»
13 years 3 months ago
Model order selection for bio-molecular data clustering
Background: Cluster analysis has been widely applied for investigating structure in bio-molecular data. A drawback of most clustering algorithms is that they cannot automatically ...
Alberto Bertoni, Giorgio Valentini
BMCBI
2007
113views more  BMCBI 2007»
13 years 3 months ago
Learning biophysically-motivated parameters for alpha helix prediction
Background: Our goal is to develop a state-of-the-art protein secondary structure predictor, with an intuitive and biophysically-motivated energy model. We treat structure predict...
Blaise Gassend, Charles W. O'Donnell, William Thie...
BMCBI
2007
166views more  BMCBI 2007»
13 years 3 months ago
Data handling strategies for high throughput pyrosequencers
Background: New high throughput pyrosequencers such as the 454 Life Sciences GS 20 are capable of massively parallelizing DNA sequencing providing an unprecedented rate of output ...
Gabriele A. Trombetti, Raoul J. P. Bonnal, Ermanno...
BMCBI
2007
164views more  BMCBI 2007»
13 years 3 months ago
Comparison of probabilistic Boolean network and dynamic Bayesian network approaches for inferring gene regulatory networks
Background: The regulation of gene expression is achieved through gene regulatory networks (GRNs) in which collections of genes interact with one another and other substances in a...
Peng Li, Chaoyang Zhang, Edward J. Perkins, Ping G...
BMCBI
2007
89views more  BMCBI 2007»
13 years 3 months ago
Combining dissimilarity based classifiers for cancer prediction using gene expression profiles
ent> <title> <p>Highlights from the Third International Society for Computational Biology (ISCB) Student Council Symposium at the Fifteenth Annual International Conf...
Ángela Blanco, Manuel Martín-Merino,...