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NAR
2010
202views more  NAR 2010»
11 years 2 months ago
dbDEPC: a database of Differentially Expressed Proteins in human Cancers
Cancer-related investigations have long been in the limelight of biomedical research. Years of effort from scientists and doctors worldwide have generated large amounts of data at...
Hong Li, Ying He, Guohui Ding, Chuan Wang, Lu Xie,...
BMCBI
2010
126views more  BMCBI 2010»
11 years 5 months ago
PETALS: Proteomic Evaluation and Topological Analysis of a mutated Locus' Signaling
Background: Colon cancer is driven by mutations in a number of genes, the most notorious of which is Apc. Though much of Apc's signaling has been mechanistically identified o...
Gürkan Bebek, Vishal Patel, Mark R. Chance
BMCBI
2004
117views more  BMCBI 2004»
11 years 7 months ago
Cancer characterization and feature set extraction by discriminative margin clustering
Background: A central challenge in the molecular diagnosis and treatment of cancer is to define a set of molecular features that, taken together, distinguish a given cancer, or ty...
Kamesh Munagala, Robert Tibshirani, Patrick O. Bro...
CANDC
2005
ACM
11 years 8 months ago
Gene selection from microarray data for cancer classification - a machine learning approach
A DNA microarray can track the expression levels of thousands of genes simultaneously. Previous research has demonstrated that this technology can be useful in the classification ...
Yu Wang 0008, Igor V. Tetko, Mark A. Hall, Eibe Fr...
BMCBI
2005
131views more  BMCBI 2005»
11 years 8 months ago
Regularized Least Squares Cancer Classifiers from DNA microarray data
Background: The advent of the technology of DNA microarrays constitutes an epochal change in the classification and discovery of different types of cancer because the information ...
Nicola Ancona, Rosalia Maglietta, Annarita D'Addab...
BMCBI
2005
167views more  BMCBI 2005»
11 years 8 months ago
Cross-platform analysis of cancer microarray data improves gene expression based classification of phenotypes
Background: The extensive use of DNA microarray technology in the characterization of the cell transcriptome is leading to an ever increasing amount of microarray data from cancer...
Patrick Warnat, Roland Eils, Benedikt Brors
NAR
2008
141views more  NAR 2008»
11 years 8 months ago
MethyCancer: the database of human DNA methylation and cancer
Cancer is ranked as one of the top killers in all human diseases and continues to have a devastating effect on the population around the globe. Current research efforts are aiming...
Ximiao He, Suhua Chang, Jiajie Zhang, Qian Zhao, H...
IJCSA
2006
138views more  IJCSA 2006»
11 years 8 months ago
An Integrated System for Cancer-Related Genes Mining from Biomedical Literatures
According to statistics, the rate of having cancer is relatively high for people in developing and developed countries. So cancer can be called as the enemy of human health. With ...
Shih-Nung Chen, Kuo-Cheng Wen
BMCBI
2006
82views more  BMCBI 2006»
11 years 8 months ago
Profiling alternatively spliced mRNA isoforms for prostate cancer classification
Background: Prostate cancer is one of the leading causes of cancer illness and death among men in the United States and world wide. There is an urgent need to discover good biomar...
Chaolin Zhang, Hai-Ri Li, Jian-Bing Fan, Jessica W...
ALIFE
2006
11 years 8 months ago
Simulating the Hallmarks of Cancer
Cancer can be viewed as the loss of cooperative cell behaviors that normally facilitate multicellularity, including the formation of tissues and organs. Hanahan and Weinberg descri...
Robert G. Abbott, Stephanie Forrest, Kenneth J. Pi...
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