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IJCBDD
2011
112views more  IJCBDD 2011»
11 years 6 months ago
A novel network model identified a 13-gene lung cancer prognostic signature
: This study presents a novel network methodology to identify prognostic gene signatures. Implication networks based on prediction logic are used to construct genome-wide coexpress...
Nancy Lan Guo, Ying-Wooi Wan, Swetha Bose, James D...
NAR
2008
114views more  NAR 2008»
11 years 11 months ago
ENDEAVOUR update: a web resource for gene prioritization in multiple species
ENDEAVOUR (http://www.esat.kuleuven.be/endeavour web; this web site is free and open to all users and there is no login requirement) is a web resource for the prioritization of ca...
Léon-Charles Tranchevent, Roland Barriot, S...
BMCBI
2006
190views more  BMCBI 2006»
11 years 11 months ago
SNPs3D: Candidate gene and SNP selection for association studies
Background: The relationship between disease susceptibility and genetic variation is complex, and many different types of data are relevant. We describe a web resource and databas...
Peng Yue, Eugene Melamud, John Moult
BMCBI
2008
120views more  BMCBI 2008»
11 years 11 months ago
A protein interaction based model for schizophrenia study
Background: Schizophrenia is a complex disease with multiple factors contributing to its pathogenesis. In addition to environmental factors, genetic factors may also increase susc...
Pei-Chun Hsu, Ueng-Cheng Yang, Kuan-Hui Shih, Chih...
BMCBI
2008
130views more  BMCBI 2008»
11 years 11 months ago
Gene Prospector: An evidence gateway for evaluating potential susceptibility genes and interacting risk factors for human diseas
Background: Millions of single nucleotide polymorphisms have been identified as a result of the human genome project and the rapid advance of high throughput genotyping technology...
Wei Yu, Anja Wulf, Tiebin Liu, Muin J. Khoury, Mar...
BMCBI
2010
154views more  BMCBI 2010»
11 years 11 months ago
Candidate gene prioritization by network analysis of differential expression using machine learning approaches
Background: Discovering novel disease genes is still challenging for diseases for which no prior knowledge - such as known disease genes or disease-related pathways - is available...
Daniela Nitsch, Joana P. Gonçalves, Fabian ...
BMCBI
2008
155views more  BMCBI 2008»
11 years 11 months ago
Extending pathways based on gene lists using InterPro domain signatures
Background: High-throughput technologies like functional screens and gene expression analysis produce extended lists of candidate genes. Gene-Set Enrichment Analysis is a commonly...
Florian Hahne, Alexander Mehrle, Dorit Arlt, Annem...
BMCBI
2010
115views more  BMCBI 2010»
11 years 11 months ago
Integration of multiple data sources to prioritize candidate genes using discounted rating system
Background: Identifying disease gene from a list of candidate genes is an important task in bioinformatics. The main strategy is to prioritize candidate genes based on their simil...
Yongjin Li, Jagdish Chandra Patra
DILS
2007
Springer
12 years 3 months ago
Accelerating Disease Gene Identification Through Integrated SNP Data Analysis
Information about small genetic variations in organisms, known as single nucleotide polymorphism (SNPs), is crucial to identify candidate genes that have a role in disease suscepti...
Paolo Missier, Suzanne M. Embury, Cornelia Hedeler...
GCB
1998
Springer
112views Biometrics» more  GCB 1998»
12 years 3 months ago
Combining diverse evidence for gene recognition in completely sequenced bacterial genomes
Analysis of a newly sequenced bacterial genome starts with identification of protein-coding genes. Functional assignment of proteins requires the exact knowledge of protein N-term...
Dmitrij Frishman, Andrey A. Mironov, Hans-Werner M...
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