GCB
2009
Springer
13 years 2 months ago
2009
Springer
Abstract: A comparative interaction detection paradigm is proposed to study the complex gene regulatory networks that control cell proliferation during development. Instead of atte...
BMCBI
2006
13 years 4 months ago
2006
Background: A transcriptional regulatory module (TRM) is a set of genes that is regulated by a common set of transcription factors (TFs). By organizing the genome into TRMs, a liv...
BMCBI
2006
13 years 4 months ago
2006
Background: Reverse-engineering regulatory networks is one of the central challenges for computational biology. Many techniques have been developed to accomplish this by utilizing...
CCE
2008
13 years 4 months ago
2008
In this paper, derivation of the optimal chemotherapy schedule is formulated and solved as a dynamic optimization problem. For this purpose two models representing the tumour grow...
BMCBI
2008
13 years 4 months ago
2008
Background: The previous studies of genome-wide expression patterns show that a certain percentage of genes are cell cycle regulated. The expression data has been analyzed in a nu...
BMCBI
2008
13 years 4 months ago
2008
Background: Eukaryotic cell cycle is a complex process and is precisely regulated at many levels. Many genes specific to the cell cycle are regulated transcriptionally and are exp...