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CMPB
2010
171views more  CMPB 2010»
11 years 18 days ago
Metabolica: A statistical research tool for analyzing metabolic networks
Steady state flux balance analysis (FBA) for cellular metabolism is used, e.g., to seek information on the activity of the different pathways under equilibrium conditions, or as a...
Jenni Heino, Daniela Calvetti, Erkki Somersalo
BMCBI
2007
126views more  BMCBI 2007»
11 years 5 months ago
Using gene expression data and network topology to detect substantial pathways, clusters and switches during oxygen deprivation
Background: Biochemical investigations over the last decades have elucidated an increasingly complete image of the cellular metabolism. To derive a systems view for the regulation...
Gunnar Schramm, Marc Zapatka, Roland Eils, Rainer ...
BMCBI
2006
104views more  BMCBI 2006»
11 years 5 months ago
MANET: tracing evolution of protein architecture in metabolic networks
Background: Cellular metabolism can be characterized by networks of enzymatic reactions and transport processes capable of supporting cellular life. Our aim is to find evolutionar...
Hee Shin Kim, Jay E. Mittenthal, Gustavo Caetano-A...
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