Sciweavers

CIBCB
2008
IEEE
13 years 6 months ago
Network motifs in context: An exploration of the evolution of oscillatory dynamics in transcriptional networks
The concept of a network motif--a small set of interacting genes which produce a predictable behaviour at the network level--has attracted considerable attention amongst network an...
Jennifer Hallinan, Anil Wipat
CIBCB
2008
IEEE
13 years 11 months ago
Temporal and structural analysis of biological networks in combination with microarray data
— We introduce a graph-based relational learning approach using graph-rewriting rules for temporal and structural analysis of biological networks changing over time. The analysis...
Chang Hun You, Lawrence B. Holder, Diane J. Cook
CIBCB
2008
IEEE
13 years 11 months ago
Classification of mouse fRNA genes using evolved neural networks
Functional RNAs (fRNAs) play a key role in gene regulation, at both the transcriptional and translational levels. Identification of fRNA genes can be difficult, given that some cla...
Mars Cheung, Gary B. Fogel
CIBCB
2008
IEEE
13 years 11 months ago
Very large scale ReliefF for genome-wide association analysis
— The genetic causes of many monogenic diseases have already been discovered. However, most common diseases are actually the result of complex nonlinear interactions between mult...
Margaret J. Eppstein, Paul Haake
CIBCB
2008
IEEE
13 years 11 months ago
Parallel multi-objective algorithms for the molecular docking problem
— Molecular docking is an essential tool for drug design. It helps the scientist to rapidly know if two molecules, respectively called ligand and receptor, can be combined togeth...
Jean-Charles Boisson, Laetitia Jourdan, El-Ghazali...
CIBCB
2008
IEEE
13 years 11 months ago
An information theoretic approach for the discovery of irregular and repetitive patterns in genomic data
sequence content at an abstract level and offers novel ways to examine the information contained in them. Our approach is an information theoretic search process which uses patter...
Willard Davis, Ananth Kalyanaraman, Diane J. Cook
CIBCB
2008
IEEE
13 years 11 months ago
Discovering novel cancer therapies: A computational modeling and search approach
— Solid tumors must recruit new blood vessels for growth and maintenance. Discovering drugs that block this tumor-induced development of new blood vessels (angiogenesis) is an im...
Arthur W. Mahoney, Brian G. Smith, Nicholas S. Fla...