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11 years 5 months ago
A Simple Approach to Ranking Differentially Expressed Gene Expression Time Courses through Gaussian Process Regression
Background: The analysis of gene expression from time series underpins many biological studies. Two basic forms of analysis recur for data of this type: removing inactive (quiet) ...
Alfredo A. Kalaitzis, Neil D. Lawrence
81views more  TR 2008»
12 years 1 months ago
The Relationship Between Confidence Intervals for Failure Probabilities and Life Time Quantiles
The failure probability of a product F(t) and the life time quantile tp are commonly used metrics in reliability applications. Confidence intervals are used to quantify the statis...
Yili Hong, William Q. Meeker, Luis A. Escobar
12 years 1 months ago
A simple and efficient sampling method for estimating AP and NDCG
We consider the problem of large scale retrieval evaluation. Recently two methods based on random sampling were proposed as a solution to the extensive effort required to judge te...
Emine Yilmaz, Evangelos Kanoulas, Javed A. Aslam
110views more  JEI 2006»
12 years 1 months ago
Empirical formula for creating error bars for the method of paired comparison
The method of paired comparison based on Thurstone's Case V of his Law of Comparative Judgments is often used as a psychophysical method to derive interval scales of perceptua...
Ethan D. Montag
165views more  BMCBI 2006»
12 years 1 months ago
Improved variance estimation of classification performance via reduction of bias caused by small sample size
Background: Supervised learning for classification of cancer employs a set of design examples to learn how to discriminate between tumors. In practice it is crucial to confirm tha...
Ulrika Wickenberg-Bolin, Hanna Göransson, M&a...
100views more  BMCBI 2010»
12 years 1 months ago
Efficiency clustering for low-density microarrays and its application to QPCR
Background: Pathway-targeted or low-density arrays are used more and more frequently in biomedical research, particularly those arrays that are based on quantitative real-time PCR...
Eric F. Lock, Ryan Ziemiecki, J. S. Marron, Dirk P...
123views more  BMCBI 2007»
12 years 1 months ago
PedGenie: meta genetic association testing in mixed family and case-control designs
Background-: PedGenie software, introduced in 2006, includes genetic association testing of cases and controls that may be independent or related (nuclear families or extended ped...
Karen Curtin, Jathine Wong, Kristina Allen-Brady, ...
12 years 3 months ago
Experimental Evaluation of Confidence Interval Procedures in Sequential Steady-State Simulation
Sequential analysis of simulation output is generally accepted as the most efficient way for securing representativeness of samples of collected observations. In this scenario a s...
Donald C. McNickle, Krzysztof Pawlikowski, Gregory...
12 years 3 months ago
Experimental performance evaluation of batch means procedures for simulation output analysis
We summarize the results of an extensive experimental performance evaluation of selected batch means procedures for building a confidence interval for a steady-state expected simu...
Natalie M. Steiger, James R. Wilson
12 years 3 months ago
An analysis of the LRE-Algorithm using Sojourn times
The classical method of evaluation of simulations surely is the batch means method, see e.g. [Bratley et al. 1987], giving confidence intervals to express the precision of the sim...
Norbert Th. Müller