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    BMCBI
    2008
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    Methylation Linear Discriminant Analysis (MLDA) for identifying differentially methylated CpG islands
    13 years 4 months ago
    Methylation Linear Discriminant Analysis (MLDA) for identifying differentially methylated CpG islands
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    Background: Hypermethylation of promoter CpG islands is strongly correlated to transcriptional gene silencing and epigenetic maintenance of the silenced state. As well as its role...
    Wei Dai, Jens M. Teodoridis, Janet Graham, Constan...
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    BMCBI
    2010
    131views more  BMCBI 2010»
    Prediction of epigenetically regulated genes in breast cancer cell lines
    13 years 4 months ago
    Prediction of epigenetically regulated genes in breast cancer cell lines
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    Background: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation o...
    Leandro A. Loss, Anguraj Sadanandam, Steffen Durin...
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