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CANDC
2002
ACM
10 years 1 months ago
Applications of Recursive Segmentation to the Analysis of DNA Sequences
Recursive segmentation is a procedure that partitions a DNA sequence into domains with a homogeneous composition of the four nucleotides A, C, G and T. This procedure can also be ...
Wentian Li, Pedro Bernaola-Galván, Fatameh ...
BMCBI
2002
134views more  BMCBI 2002»
10 years 1 months ago
CoreGenes: A computational tool for identifying and cataloging "core" genes in a set of small genomes
Background: Improvements in DNA sequencing technology and methodology have led to the rapid expansion of databases comprising DNA sequence, gene and genome data. Lower operational...
Nikhat Zafar, Raja Mazumder, Donald Seto
BMCBI
2004
105views more  BMCBI 2004»
10 years 1 months ago
eL-DASionator: an LDAS upload file generator
Background: The Distributed Annotation System (DAS) allows merging of DNA sequence annotations from multiple sources and provides a single annotation view. A straightforward way t...
Vincent Nègre, Christoph Grunau
BMCBI
2004
146views more  BMCBI 2004»
10 years 1 months ago
The InDeVal insertion/deletion evaluation tool: a program for finding target regions in DNA sequences and for aiding in sequence
Background: The program InDeVal was originally developed to help researchers find known regions of insertion/deletion activity (with the exception of isolated single-base indels) ...
Sierra D. Stoneberg Holt, Jason A. Holt
BMCBI
2004
81views more  BMCBI 2004»
10 years 1 months ago
Few amino acid positions in rpoB are associated with most of the rifampin resistance in Mycobacterium tuberculosis
Background: Mutations in rpoB, the gene encoding the subunit of DNA-dependent RNA polymerase, are associated with rifampin resistance in Mycobacterium tuberculosis. Several studi...
Michael P. Cummings, Mark R. Segal
BMCBI
2005
133views more  BMCBI 2005»
10 years 1 months ago
Ab initio identification of putative human transcription factor binding sites by comparative genomics
Background: Understanding transcriptional regulation of gene expression is one of the greatest challenges of modern molecular biology. A central role in this mechanism is played b...
Davide Corà, Carl Herrmann, Christoph Diete...
ARTMED
2005
87views more  ARTMED 2005»
10 years 1 months ago
Fuzzy attributes of a DNA complex: Development of a fuzzy inference engine for codon-"junk" codon delineation
Codons refer to those parts in a DNA complex encoded towards forming a desired set of proteins. Also coexist in the DNA are noncodons (or "junk" codons) whose functions ...
Tomás Arredondo Vidal, Perambur S. Neelakan...
BMCBI
2006
132views more  BMCBI 2006»
10 years 1 months ago
Genome-wide DNA polymorphism analyses using VariScan
Background: DNA sequence polymorphisms analysis can provide valuable information on the evolutionary forces shaping nucleotide variation, and provides an insight into the function...
Stephan Hutter, Albert J. Vilella, Julio Rozas
BMCBI
2006
137views more  BMCBI 2006»
10 years 1 months ago
Sigma: multiple alignment of weakly-conserved non-coding DNA sequence
Background: Existing tools for multiple-sequence alignment focus on aligning protein sequence or protein-coding DNA sequence, and are often based on extensions to Needleman-Wunsch...
Rahul Siddharthan
BMCBI
2006
99views more  BMCBI 2006»
10 years 1 months ago
MAGIC-SPP: a database-driven DNA sequence processing package with associated management tools
Background: Processing raw DNA sequence data is an especially challenging task for relatively small laboratories and core facilities that produce as many as 5000 or more DNA seque...
Chun Liang, Feng Sun, Haiming Wang, Junfeng Qu, Ro...
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