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BMCBI
2005
96views more  BMCBI 2005»
13 years 4 months ago
Comparison of codon usage measures and their applicability in prediction of microbial gene expressivity
Background: There are a number of methods (also called: measures) currently in use that quantify codon usage in genes. These measures are often influenced by other sequence proper...
Fran Supek, Kristian Vlahovicek
BMCBI
2005
86views more  BMCBI 2005»
13 years 4 months ago
Confirmation of human protein interaction data by human expression data
Background: With microarray technology the expression of thousands of genes can be measured simultaneously. It is well known that the expression levels of genes of interacting pro...
Andreas Hahn, Jörg Rahnenführer, Priti T...
JCST
2008
124views more  JCST 2008»
13 years 4 months ago
Clustering by Pattern Similarity
The task of clustering is to identify classes of similar objects among a set of objects. The definition of similarity varies from one clustering model to another. However, in most ...
Haixun Wang, Jian Pei
BMCBI
2007
122views more  BMCBI 2007»
13 years 4 months ago
Dissecting complex transcriptional responses using pathway-level scores based on prior information
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
Harmen J. Bussemaker, Lucas D. Ward, André ...
BMCBI
2006
103views more  BMCBI 2006»
13 years 4 months ago
Probe-level linear model fitting and mixture modeling results in high accuracy detection of differential gene expression
Background: The identification of differentially expressed genes (DEGs) from Affymetrix GeneChips arrays is currently done by first computing expression levels from the low-level ...
Sébastien Lemieux
BMCBI
2006
125views more  BMCBI 2006»
13 years 4 months ago
Evaluating different methods of microarray data normalization
Background: With the development of DNA hybridization microarray technologies, nowadays it is possible to simultaneously assess the expression levels of thousands to tens of thous...
André Fujita, João Ricardo Sato, Leo...
BMCBI
2006
165views more  BMCBI 2006»
13 years 4 months ago
A stable gene selection in microarray data analysis
Background: Microarray data analysis is notorious for involving a huge number of genes compared to a relatively small number of samples. Gene selection is to detect the most signi...
Kun Yang, Zhipeng Cai, Jianzhong Li, Guohui Lin
BIOINFORMATICS
2006
118views more  BIOINFORMATICS 2006»
13 years 4 months ago
A probabilistic dynamical model for quantitative inference of the regulatory mechanism of transcription
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Magnus Rattray, Neil D. Lawrenc...
CGF
2008
142views more  CGF 2008»
13 years 4 months ago
Visualizing Genome Expression and Regulatory Network Dynamics in Genomic and Metabolic Context
DNA microarrays are used to measure the expression levels of thousands of genes simultaneously. In a time series experiment, the gene expressions are measured as a function of tim...
Michel A. Westenberg, Sacha A. F. T. van Hijum, Os...
BMCBI
2008
126views more  BMCBI 2008»
13 years 4 months ago
ISOL@: an Italian SOLAnaceae genomics resource
Background: Present-day `-omics' technologies produce overwhelming amounts of data which include genome sequences, information on gene expression (transcripts and proteins) a...
Maria Luisa Chiusano, Nunzio D'Agostino, Alessandr...