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BIOINFORMATICS
2006
135views more  BIOINFORMATICS 2006»
13 years 3 months ago
Effective similarity measures for expression profiles
It is commonly accepted that genes with similar expression profiles are functionally related. However, there are many ways one can measure the similarity of expression profiles, a...
Golan Yona, William Dirks, Shafquat Rahman, David ...
BMCBI
2007
140views more  BMCBI 2007»
13 years 3 months ago
Prediction potential of candidate biomarker sets identified and validated on gene expression data from multiple datasets
Background: Independently derived expression profiles of the same biological condition often have few genes in common. In this study, we created populations of expression profiles...
Michael Gormley, William Dampier, Adam Ertel, Bilg...
BMCBI
2008
135views more  BMCBI 2008»
13 years 3 months ago
Inferring the role of transcription factors in regulatory networks
Background: Expression profiles obtained from multiple perturbation experiments are increasingly used to reconstruct transcriptional regulatory networks, from well studied, simple...
Philippe Veber, Carito Guziolowski, Michel Le Borg...
BMCBI
2010
85views more  BMCBI 2010»
13 years 3 months ago
Robust test method for time-course microarray experiments
Background: In a time-course microarray experiment, the expression level for each gene is observed across a number of time-points in order to characterize the temporal trajectorie...
Insuk Sohn, Kouros Owzar, Stephen L. George, Sujon...
BMCBI
2008
121views more  BMCBI 2008»
13 years 3 months ago
GeneTrailExpress: a web-based pipeline for the statistical evaluation of microarray experiments
Background: High-throughput methods that allow for measuring the expression of thousands of genes or proteins simultaneously have opened new avenues for studying biochemical proce...
Andreas Keller, Christina Backes, Maher Al-Awadhi,...
BMCBI
2010
115views more  BMCBI 2010»
13 years 3 months ago
Importance of replication in analyzing time-series gene expression data: Corticosteroid dynamics and circadian patterns in rat l
Background: Microarray technology is a powerful and widely accepted experimental technique in molecular biology that allows studying genome wide transcriptional responses. However...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
BIOINFORMATICS
2007
195views more  BIOINFORMATICS 2007»
13 years 3 months ago
Context-dependent clustering for dynamic cellular state modeling of microarray gene expression
Motivation: High-throughput expression profiling allows researchers to study gene activities globally. Genes with similar expression profiles are likely to encode proteins that ma...
Shinsheng Yuan, Ker-Chau Li
BIBE
2001
IEEE
13 years 7 months ago
Gene Classification using Expression Profiles: A Feasibility Study
As various genome sequencing projects have already been completed or are near completion, genome researchers are shifting their focus from structural genomics to functional genomi...
Michihiro Kuramochi, George Karypis