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BMCBI
2007
103views more  BMCBI 2007»
13 years 4 months ago
A comprehensive evaluation of SAM, the SAM R-package and a simple modification to improve its performance
Background: The Significance Analysis of Microarrays (SAM) is a popular method for detecting significantly expressed genes and controlling the false discovery rate (FDR). Recently...
Shunpu Zhang
BMCBI
2008
105views more  BMCBI 2008»
13 years 4 months ago
Using the longest significance run to estimate region-specific p-values in genetic association mapping studies
Background: Association testing is a powerful tool for identifying disease susceptibility genes underlying complex diseases. Technological advances have yielded a dramatic increas...
Ie-Bin Lian, Yi-Hsien Lin, Ying-Chao Lin, Hsin-Cho...
BMCBI
2007
120views more  BMCBI 2007»
13 years 4 months ago
Re-sampling strategy to improve the estimation of number of null hypotheses in FDR control under strong correlation structures
Background: When conducting multiple hypothesis tests, it is important to control the number of false positives, or the False Discovery Rate (FDR). However, there is a tradeoff be...
Xin Lu, David L. Perkins
RECOMB
2007
Springer
14 years 4 months ago
Peptide Retention Time Prediction Yields Improved Tandem Mass Spectrum Identification for Diverse Chromatography Conditions
Most tandem mass spectrum identification algorithms use information only from the final spectrum, ignoring precursor information such as peptide retention time (RT). Efforts to exp...
Aaron A. Klammer, Xianhua Yi, Michael J. MacCoss, ...
ICIP
2008
IEEE
14 years 6 months ago
Motion detection with false discovery rate control
Visual surveillance applications such as object identification, object tracking, and anomaly detection require reliable motion detection as an initial processing step. Such a dete...
David A. Castañon, J. Mike McHugh, Janusz K...