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NAR
2011
238views Computer Vision» more  NAR 2011»
12 years 11 months ago
COMBREX: a project to accelerate the functional annotation of prokaryotic genomes
COMBREX (http://combrex.bu.edu) is a project to increase the speed of the functional annotation of new bacterial and archaeal genomes. It consists of a database of functional pred...
Richard J. Roberts, Yi-Chien Chang, Zhenjun Hu, Jo...
BMCBI
2010
155views more  BMCBI 2010»
13 years 1 months ago
BrEPS: a flexible and automatic protocol to compute enzyme-specific sequence profiles for functional annotation
Background: Models for the simulation of metabolic networks require the accurate prediction of enzyme function. Based on a genomic sequence, enzymatic functions of gene products a...
Constantin Bannert, A. Welfle, C. aus dem Spring, ...
BMCBI
2005
114views more  BMCBI 2005»
13 years 4 months ago
AutoFACT: An Automatic Functional Annotation and Classification Tool
Background: Assignment of function to new molecular sequence data is an essential step in genomics projects. The usual process involves similarity searches of a given sequence aga...
Liisa B. Koski, Michael W. Gray, B. Franz Lang, Ge...
BMCBI
2005
92views more  BMCBI 2005»
13 years 4 months ago
FIGENIX: Intelligent automation of genomic annotation: expertise integration in a new software platform
Background: Two of the main objectives of the genomic and post-genomic era are to structurally and functionally annotate genomes which consists of detecting genes' position a...
Philippe Gouret, Vérane Vitiello, Nathalie ...
BMCBI
2008
100views more  BMCBI 2008»
13 years 4 months ago
High-precision high-coverage functional inference from integrated data sources
Background: Information obtained from diverse data sources can be combined in a principled manner using various machine learning methods to increase the reliability and range of k...
Bolan Linghu, Evan S. Snitkin, Dustin T. Holloway,...
BMCBI
2010
141views more  BMCBI 2010»
13 years 4 months ago
BioPhysConnectoR: Connecting Sequence Information and Biophysical Models
Background: One of the most challenging aspects of biomolecular systems is the understanding of the coevolution in and among the molecule(s). A complete, theoretical picture of th...
Franziska Hoffgaard, Philipp Weil, Kay Hamacher
GFKL
2005
Springer
141views Data Mining» more  GFKL 2005»
13 years 10 months ago
On External Indices for Mixtures: Validating Mixtures of Genes
Mixture models represent results of gene expression cluster analysis in a more natural way than ’hard’ partitions. This is also true for the representation of gene labels, such...
Ivan G. Costa, Alexander Schliep