238views Computer Vision» more  NAR 2011»
9 years 1 months ago
COMBREX: a project to accelerate the functional annotation of prokaryotic genomes
COMBREX ( is a project to increase the speed of the functional annotation of new bacterial and archaeal genomes. It consists of a database of functional pred...
Richard J. Roberts, Yi-Chien Chang, Zhenjun Hu, Jo...
155views more  BMCBI 2010»
9 years 4 months ago
BrEPS: a flexible and automatic protocol to compute enzyme-specific sequence profiles for functional annotation
Background: Models for the simulation of metabolic networks require the accurate prediction of enzyme function. Based on a genomic sequence, enzymatic functions of gene products a...
Constantin Bannert, A. Welfle, C. aus dem Spring, ...
114views more  BMCBI 2005»
9 years 6 months ago
AutoFACT: An Automatic Functional Annotation and Classification Tool
Background: Assignment of function to new molecular sequence data is an essential step in genomics projects. The usual process involves similarity searches of a given sequence aga...
Liisa B. Koski, Michael W. Gray, B. Franz Lang, Ge...
92views more  BMCBI 2005»
9 years 6 months ago
FIGENIX: Intelligent automation of genomic annotation: expertise integration in a new software platform
Background: Two of the main objectives of the genomic and post-genomic era are to structurally and functionally annotate genomes which consists of detecting genes' position a...
Philippe Gouret, Vérane Vitiello, Nathalie ...
100views more  BMCBI 2008»
9 years 7 months ago
High-precision high-coverage functional inference from integrated data sources
Background: Information obtained from diverse data sources can be combined in a principled manner using various machine learning methods to increase the reliability and range of k...
Bolan Linghu, Evan S. Snitkin, Dustin T. Holloway,...
141views more  BMCBI 2010»
9 years 7 months ago
BioPhysConnectoR: Connecting Sequence Information and Biophysical Models
Background: One of the most challenging aspects of biomolecular systems is the understanding of the coevolution in and among the molecule(s). A complete, theoretical picture of th...
Franziska Hoffgaard, Philipp Weil, Kay Hamacher
141views Data Mining» more  GFKL 2005»
10 years 15 days ago
On External Indices for Mixtures: Validating Mixtures of Genes
Mixture models represent results of gene expression cluster analysis in a more natural way than ’hard’ partitions. This is also true for the representation of gene labels, such...
Ivan G. Costa, Alexander Schliep