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GCB
2009
Springer
196views Biometrics» more  GCB 2009»
11 years 6 months ago
Comparative Generalized Logic Modeling Reveals Differential Gene Interactions during Cell Cycle Exit in Drosophila Wing Developm
Abstract: A comparative interaction detection paradigm is proposed to study the complex gene regulatory networks that control cell proliferation during development. Instead of atte...
Mingzhou Song, Chung-Chien Hong, Yang Zhang, Laura...
GCB
2009
Springer
193views Biometrics» more  GCB 2009»
11 years 12 months ago
Integration and Visualisation of Multimodal Biological Data
: Understanding complex biological systems requires data from manifold biological levels. Often this data is analysed in some meaningful context, for example, by integrating it int...
Hendrik Rohn, Christian Klukas, Falk Schreiber
GCB
2009
Springer
154views Biometrics» more  GCB 2009»
12 years 1 days ago
Comparative Identification of Differential Interactions from Trajectories of Dynamic Biological Networks
Abstract: It is often challenging to reconstruct accurately a complete dynamic biological network due to the scarcity of data collected in cost-effective experiments. This paper ad...
Zhengyu Ouyang, Mingzhou Song
GCB
2009
Springer
139views Biometrics» more  GCB 2009»
12 years 1 days ago
Graph-Kernels for the Comparative Analysis of Protein Active Sites
Abstract: Graphs are often used to describe and analyze the geometry and physicochemical composition of biomolecular structures, such as chemical compounds and protein active sites...
Thomas Fober, Marco Mernberger, Ralph Moritz, Eyke...
GCB
2009
Springer
105views Biometrics» more  GCB 2009»
12 years 2 months ago
Maximum Likelihood Estimation of Weight Matrices for Targeted Homology Search
: Genome annotation relies to a large extent on the recognition of homologs to already known genes. The starting point for such protocols is a collection of known sequences from on...
Peter Menzel, Jan Gorodkin, Peter F. Stadler
GCB
2009
Springer
141views Biometrics» more  GCB 2009»
12 years 2 months ago
Discovering Temporal Patterns of Differential Gene Expression in Microarray Time Series
: A wealth of time series of microarray measurements have become available over recent years. Several two-sample tests for detecting differential gene expression in these time seri...
Oliver Stegle, Katherine J. Denby, David L. Wild, ...
GCB
2009
Springer
180views Biometrics» more  GCB 2009»
12 years 2 months ago
2D Projections of RNA Folding Landscapes
Abstract: The analysis of RNA folding landscapes yields insights into the kinetic folding behavior not available from classical structure prediction methods. This is especially imp...
Ronny Lorenz, Christoph Flamm, Ivo L. Hofacker
GCB
2009
Springer
481views Biometrics» more  GCB 2009»
12 years 2 months ago
CUDA-based Multi-core Implementation of MDS-based Bioinformatics Algorithms
: Solving problems in bioinformatics often needs extensive computational power. Current trends in processor architecture, especially massive multi-core processors for graphic cards...
Thilo Fester, Falk Schreiber, Marc Strickert
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