BMCBI
2005
13 years 4 months ago
2005
Background: Gender differences in gene expression were estimated in liver samples from 9 males and 9 females. The study tested 31,110 genes for a gender difference using a design ...
BMCBI
2005
13 years 4 months ago
2005
Background: The extensive use of DNA microarray technology in the characterization of the cell transcriptome is leading to an ever increasing amount of microarray data from cancer...
BMCBI
2005
13 years 4 months ago
2005
Background: A promising direction in the analysis of gene expression focuses on the changes in expression of specific predefined sets of genes that are known in advance to be rela...
BMCBI
2005
13 years 4 months ago
2005
Background: A common feature of microarray experiments is the occurence of missing gene expression data. These missing values occur for a variety of reasons, in particular, becaus...
BMCBI
2005
13 years 4 months ago
2005
Background: Cells react to changing intra- and extracellular signals by dynamically modulating complex biochemical networks. Cellular responses to extracellular signals lead to ch...
BMCBI
2005
2005
Phylogenetic reconstruction of ancestral character states for gene expression and mRNA splicing data
13 years 4 months ago
Background: As genomes evolve after speciation, gene content, coding sequence, gene expression, and splicing all diverge with time from ancestors with close relatives. A minimum e...
BMCBI
2005
13 years 4 months ago
2005
Background: Quality-control is an important issue in the analysis of gene expression microarrays. One type of problem is regional bias, in which one region of a chip shows artifac...
BMCBI
2005
13 years 4 months ago
2005
Background: A large number of papers have been published on analysis of microarray data with particular emphasis on normalization of data, detection of differentially expressed ge...
BMCBI
2005
13 years 4 months ago
2005
Background: Interpretation of simple microarray experiments is usually based on the fold-change of gene expression between a reference and a "treated" sample where the t...
BMCBI
2005
13 years 4 months ago
2005
Background: In testing for differential gene expression involving multiple serial analysis of gene expression (SAGE) libraries, it is critical to account for both between and with...