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BMCBI
2004
252views more  BMCBI 2004»
8 years 7 months ago
Applying Support Vector Machines for Gene ontology based gene function prediction
Background: The current progress in sequencing projects calls for rapid, reliable and accurate function assignments of gene products. A variety of methods has been designed to ann...
Arunachalam Vinayagam, Rainer König, Jutta Mo...
BMCBI
2004
126views more  BMCBI 2004»
8 years 7 months ago
Visualization and analysis of microarray and gene ontology data with treemaps
Background: The increasing complexity of genomic data presents several challenges for biologists. Limited computer monitor views of data complexity and the dynamic nature of data ...
Eric H. Baehrecke, Niem Dang, Ketan Babaria, Ben S...
BMCBI
2005
113views more  BMCBI 2005»
8 years 7 months ago
Systematic survey reveals general applicability of "guilt-by-association" within gene coexpression networks
Background: Biological processes are carried out by coordinated modules of interacting molecules. As clustering methods demonstrate that genes with similar expression display incr...
Cecily J. Wolfe, Isaac S. Kohane, Atul J. Butte
BMCBI
2005
159views more  BMCBI 2005»
8 years 7 months ago
Columba: an integrated database of proteins, structures, and annotations
Background: Structural and functional research often requires the computation of sets of protein structures based on certain properties of the proteins, such as sequence features,...
Silke Trißl, Kristian Rother, Heiko Mül...
BMCBI
2005
112views more  BMCBI 2005»
8 years 7 months ago
Integration of the Gene Ontology into an object-oriented architecture
Background: To standardize gene product descriptions, a formal vocabulary defined as the Gene Ontology (GO) has been developed. GO terms have been categorized into biological proc...
Daniel Shegogue, W. Jim Zheng
BMCBI
2005
154views more  BMCBI 2005»
8 years 7 months ago
GObar: A Gene Ontology based analysis and visualization tool for gene sets
Background: Microarray experiments, as well as other genomic analyses, often result in large gene sets containing up to several hundred genes. The biological significance of such ...
Jason S. M. Lee, Gurpreet Katari, Ravi Sachidanand...
NAR
2008
94views more  NAR 2008»
8 years 7 months ago
The Gene Ontology project in 2008
The Gene Ontology (GO) project (http://www.gene ontology.org/) provides a set of structured, controlled vocabularies for community use in annotating genes, gene products and seque...
BMCBI
2007
140views more  BMCBI 2007»
8 years 7 months ago
Evaluation of high-throughput functional categorization of human disease genes
Background: Biological data that are well-organized by an ontology, such as Gene Ontology, enables high-throughput availability of the semantic web. It can also be used to facilit...
James L. Chen, Yang Liu, Lee T. Sam, Jianrong Li, ...
BMCBI
2007
123views more  BMCBI 2007»
8 years 7 months ago
GO for gene documents
Annotating genes and their products with Gene Ontology codes is an important area of research. One approach for doing this is to use the information available about these genes in...
Padmini Srinivasan, Xin Ying Qiu
BMCBI
2007
166views more  BMCBI 2007»
8 years 7 months ago
How to decide which are the most pertinent overly-represented features during gene set enrichment analysis
Background: The search for enriched features has become widely used to characterize a set of genes or proteins. A key aspect of this technique is its ability to identify correlati...
Roland Barriot, David J. Sherman, Isabelle Dutour
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